Dr Maggie Wang obtained her Bachelor degree (honour) in Physics of the Hong Kong University of Science and Technology (HKUST), and her Doctor in Philosophy degree in Statistics from ISOM department of the HKUST. She joined the Chinese University of Hong Kong as a Research Assistant Professor in 2011. Since 2015 she is an Assistant Professor in the JC School of Public Health and Primary Care. Dr Wang is awarded the SH Ho Visiting Professorship Exchange Programme to Stanford University in 2016. She is the Principle Investigator of multiple research grants, including the Hong Kong RGC-GRF, HMRF, and the National Science Foundation of China (NSFC) Projects. She is a member of the Centre for Clinical Research and Biostatistics (CCRB) and the Assistant Director of the MSc program of Epidemiology and Biostatistics.
Statistical Genetics Research Unit (CCRB-Statgene) website: http://www2.ccrb.cuhk.edu.hk/statgene
Website at SPHPC: http://www.sphpc.cuhk.edu.hk/maggiew
Research Interests
- Bioinformatics and statistical genetics: develop new statistical methods and algorithms that provide an accurate measure for gene-gene or gene-environmental interactions effects, and incorporate interactions in disease classification problem. Representative publications: Bioinformatics 2017,2012; Nucleic Acids Research 2016
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Infectious diseases genetic epidemiology: model the pattern of infectious disease epidemics at a population level and genetic level, and model genetic sequence evolution. Representative publications: Journal of Infection 2016, 2020
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Statistical collaborations: from genetic and biomedical data analysis to large multinational epidemiological data analysis. Representative publications: Oncogene 2015; Cancer Research 2016, Microbiome 2020
Software developed
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W-test: for the main effect and SNP-SNP interaction association testing in GWAS data (software page)
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ZFA: for rare variant association tests in NGS data (software)
Book Chapter
“Genetic Test, Risk Prediction Model, and Genetic Counselling”, with Haoyi Weng, Book Title: Translational Informatics in Smart Healthcare, Springer, 2016.
“W-test for genetic epistasis testing”, with Rui Sun, Haoyi Weng, Book Title: Methods in Molecular Biology, Humana Press (Springer), 2019
Publications (* Corresponding author; + Co-first author, Representative work in boldface)
1. Xiaoxuan Xia, William K.K. Wu, Sunny H. Wong, Dabin Liu, Thomas N.Y. Kwong, Geicho Nakatsu, Pearlly S. Yan, Yu-Ming Chuang, Michael W.Y. Chan, Olabisi O. Coker, Zigui Chen, Yun K. Yeoh, Liuyang Zhao, Xiansong Wang, Wing Y. Cheng, Matthew T.V. Chan, Paul K.S. Chan, Joseph J.Y. Sung, Maggie H Wang*, Jun Yu* (2020) (co-corresponding author) Bacteria pathogens drive host colonic epithelial cell promoter hypermethylation of tumour suppressor genes in colorectal cancer. Microbiome. IF=10.465, Rank 7/149 in Microbiology.
2. Shi Zhao, Jingzhi Lou, Lirong Cao, Zigui Chen, Renee WY Chan, Marc KC Chong, Benny CY Zee, Paul KS Chan, Maggie H Wang* (2020) Quantifying the importance of the key sites on haemagglutinin in determining the selection advantage of influenza virus: using A/H3N2 as an example. Journal of Infection. (2020). IF = 5.099. Rank 19/286 in Infectious Diseases. doi.org/10.1016/j.jinf.2020.05.066
3. Shi Zhao, Salihu S Musa, Qianying Lin, Jinjun Ran, Guangpu Yang, Weiming Wang, Yijun Lou, Lin Yang, Daozhou Gao, Daihai He, Maggie H Wang (2020) Preliminary estimation of the basic reproduction number of novel coronavirus (2019-nCoV) in China, from 2019 to 2020: A data-driven analysis in the early phase of the outbreak. International Journal of Infectious Diseases. IF= 3.420. doi: 10.1016/j.ijid.2020.01.050, Rank 51/286 in Infectious Diseases.
4. Qianying Lin, Shi Zhao, Daozhou Gao, Yijun Lou, Shu Yang, Salihu S Musa, Maggie H Wang, Yongli Cai, Weiming Wang, Lin Yang, Daihai He (2020) A conceptual model for the coronavirus disease 2019 (COVID-19) outbreak in Wuhan, China with individual reaction and governmental action. International Journal Of Infectious Diseases, 93, 211-216. IF = 3.420. (Cited 117 times as of 2020/06/01) Doi: https://doi.org/10.1016/j.ijid.2020.02.058. Rank 51/286 in Infectious Diseases.
5. Shi Zhao, Salihu S Musa, Qianying Lin, Jinjun Ran, Guangpu Yang, Weiming Wang, Yijun Lou, Lin Yang, Daozhou Gao, Daihai He, Maggie H Wang (2020) Estimating of the unreported number of novel coronavirus (2019-nCoV) cases in China in the first half of January 2020: A data-driven modelling. Journal of Clinical Medicine. IF= 5.8. Doi: 10.3390/jcm9020388. Ranking 15/154 in Medicine, General & Internal
6. Chong KC, Cheng W, Zhao S, Ling F, Mohammad KN, Wang MH, Zee BC, Wei L, Xiong X, Liu H, Wang J. Monitoring disease transmissibility of 2019 novel coronavirus disease in Zhejiang, China. International Journal of Infectious Diseases. 2020 Jul 1;96:128-30. IF= 3.420. Rank 51/286 in Infectious Diseases.
7. Shi Zhao, Zian Zhuang, Peihua Cao, Jinjun Ran, Daozhou Gao, Yijun Lou, Lin Yang, Yongli Cai, Weiming Wang, Daihai He, Maggie H Wang (2020). Quantifying the association between domestic travel and the exportation of novel coronavirus (2019-nCoV) cases from Wuhan, China in 2020: a correlational analysis. Journal of Travel Medicine. IF = 4.155. Ranking 25/160 in Medicine, General & Internal. https://doi.org/10.1093/jtm/taaa022
8. Zhao S, Cao P, Gao D, Zhuang Z, Cai Y, Ran J, Chong MK, Wang K, Lou Y, Wang W, Yang L, He D, Wang MH (2020). Serial interval in determining the estimation of reproduction number of the novel coronavirus disease (COVID-19) during the early outbreak. Journal of Travel Medicine. 2020 Mar. https://doi.org/10.1093/jtm/taaa033. IF = 4.155. Ranking 25/160 in Medicine, General & Internal.
9. He D, Zhao S, Lin Q, Zhuang Z, Cao P, Wang MH, Yang L (2020). The relative transmissibility of asymptomatic cases among close contacts. International Journal of Infectious Diseases. 2020 Apr 18. IF= 3.420. Rank 51/286 in Infectious Diseases.
10. Zhao S, Cao P, Chong MK, Gao D, Lou Y, Ran J, Wang K, Wang W, Yang L, He D, Wang MH (2020). COVID-19 and gender-specific difference: Analysis of public surveillance data in Hong Kong and Shenzhen, China, from January 10 to February 15, 2020. Infection Control & Hospital Epidemiology. 2020 Mar 9:1-2.
11. Tang X, Zhao S, He D, Yang L, Wang MH, Li Y, Mei S, Zou X (2020). Positive RT-PCR tests among discharged COVID-19 patients in Shenzhen, China. Infection Control & Hospital Epidemiology. 2020 Apr 16:1-7.
12. Wang K, Zhao S, Liao Y, Zhao T, Wang X, Zhang X, Jiao H, Li H, Yin Y, Wang MH, Xiao L. Estimating the serial interval of the novel coronavirus disease (COVID‐19) based on the public surveillance data in Shenzhen, China from January 19 to February 22, 2020. Transboundary and Emerging Diseases. Q1 in Medicine. 2020 May 26. IF=3.47.
13. Chan LL, Wong AY, Wang MH. Associations between sport participation and knee symptoms: a cross-sectional study involving 3053 undergraduate students. BMC Sports Science, Medicine and Rehabilitation. 2020 Dec;12:1-8. IF=1.50
14. Chong KC, Liang J, Jia KM, Kobayashi N, Wang MH, Wei L, Lau SY, Sumi A (2020). Latitudes mediate the association between influenza activity and meteorological factors: A nationwide modelling analysis in 45 Japanese prefectures from 2000 to 2018. Science of The Total Environment. 2020 Feb 10;703:134727. IF = 5.899. Rank 27/242 in Environmental Science. Doi: 10.1016/j.scitotenv.2019.134727
15. H Zheng, KM Jia, R Sun, P Hu, MH Wang, BCY Zee, W Liang, KC Chong (2020) Epidemiological changes in measles infections in southern China between 2009 and 2016: a retrospective database analysis. BMC Infectious Diseases, 20(1), 1-10. IF = 2.565 Doi: 10.1186/s12879-020-4919-x
16. Lloyd Long Yu Chan, Arnold Yu Lok Wong, Maggie Haitian Wang, Kin Cheung, Dino Samartzis., (2020). The prevalence of neck pain and associated risk factors among undergraduate students: A large-scale cross-sectional study. International Journal Of Industrial Ergonomics, 76, 102934. IF = 1.571 Doi: https://doi.org/10.1016/j.ergon.2020.102934
17. Chong KC, Hu P, Chan SY, Liang W, Mohammad KN, Sun R, Wang MH, Zee BC, Shi D, Zheng H (2020). Were infections in migrants associated with the resurgence of measles epidemic during 2013–2014 in southern China? A retrospective data analysis. International Journal of Infectious Diseases. 2020 Jan 1;90:77-83. IF= 3.420 Doi: 10.1016/j.ijid.2019.10.014.
18. Li J, Ogorodova LM, Mahesh PA, Wang MH, Fedorova OS, Leung TF, Fernandez-Rivas M, Mills EC, Potts J, Kummeling I, Versteeg SA, van Ree R, Yazdanbakhsh M, Burney PGJ, Wong GWK. (2019). Comparative study of food allergies in children from China, India and Russia: The EuroPrevall-INCO surveys. 2019 Dec 16. Journal of Allergy and Clinical Immunology. IF= 13.258 Doi: 10.1016/j.jaip.2019.11.042.
19. Rui Sun, Xiaoxuan Xia, Ka Chun Chong, Benny Chung-Ying Zee, William Ka Kei Wu, Maggie Haitian Wang* (2019) wtest: an integrated R package for genetic epistasis testing, BMC Medical Genomics. IF= 2.632 Doi: https://doi.org/10.1186/s12920-019-0638-9.
20. Lau SY, Chen E, Wang M, Cheng W, Zee BC, Han X, Yu Z, Sun R, Chong KC, Wang X. Association between meteorological factors, spatiotemporal effects, and prevalence of influenza A subtype H7 in environmental samples in Zhejiang province, China. Science of The Total Environment. 2019 Jan 31. IF= 5.899. Rank 27/242 in Environmental Science. Doi: 10.1016/j.scitotenv.2019.01.403
21. Chong KC, Leung CC, Yew WW, Zee BC, Tam GC, Wang MH, Jia KM, Chung PH, Lau SY, Han X, Yeoh EK. Mathematical modelling of the impact of treating latent tuberculosis infection in the elderly in a city with intermediate tuberculosis burden. Scientific reports. 2019 Mar 19;9(1):4869. IF= 4.116 Doi: https://doi.org/10.1038/s41598-019-41256-4
22. Cheng W, Chong KC, Lau SY, Wang X, Yu Z, Liu S, Wang M, Pan J, Chen E. Comparison of avian influenza virus contamination in the environment before and after massive poultry H5/H7 vaccination in Zhejiang province, China. In Open Forum Infectious Diseases 2019 Apr 24 (Vol. 6, No. 6, p. ofz197). US: Oxford University Press. IF= 2.695 Doi: https://doi.org/10.1093/ofid/ofz197
23. Teoh JY, Chan CK, Wang MH, Leung CH, Chan ES, Chiu PK, Yee CH, Wong HM, Hou SS, Ng CF. Transurethral resection of prostate for acute urinary retention is linked to shorter survival in younger men. Asian journal of andrology. 2019 Jan 15. IF = 2.530 Doi: 10.4103/aja.aja_101_18.
24. Chan MC, Wang MH, Chen Z, Hui DS, Kwok AK, Yeung AC, Liu KM, Yeoh YK, Lee N, Chan PK. Frequent Genetic Mismatch between Vaccine Strains and Circulating Seasonal Influenza Viruses, Hong Kong, China, 1996–2012. Emerging infectious diseases. 2018 Oct;24(10):1825. IF = 7.422. Rank 4/88 in Infectious Disease Doi: 10.3201/eid2410.180652
25. Maggie Haitian Wang*, Heather Cordell, Kristel Van Steen (2019) Statistical Methods for Genome-wide Association Studies. Seminars in Cancer Biology. 2019 April. Rank 13/223 in Oncology. IF = 10.198 Doi: 10.1016/j.semcancer.2018.04.008
26. Chong KC, Rui Y, Liu Y, Zhou T, Jia K, Wang MH, Mohammad KN, He H. Early Waning of Maternal Measles Antibodies in Infants in Zhejiang Province, China: A Comparison of Two Cross-Sectional Serosurveys. International journal of environmental research and public health. 2019 Jan;16(23):4680. IF = 2.619 Doi: 10.3390/ijerph16234680
27. Ka Chun Chong, Chi Zhang, Katherine Min Jia, Benny Chung Ying Zee, Tongyong Luo, Lei Wang, Greta Chun Huen Tam, Riyang Sun, Maggie Haitian Wang, Xuhua Guan. Targeting Adults for Supplementary Immunization Activities of Measles Control in Central China: A Mathematical Modelling Study. Sci Rep 8, 16124 (2018). IF = 4.122 Doi: https://doi.org/10.1038/s41598-018-34461-0
28. William KK Wu, Rui Sun, Tao Zuo, Yuanyuan Tian, Zhirong Zeng, Jeffery Ho, Justin CY Wu, Francis KL Chan, Matthew TV Chan, Jun Yu, Joseph JY Sung, Sunny H Wong, Maggie H Wang*, Siew C Ng* (2018) A novel susceptibility locus in MST 1 and gene‐gene interaction network for Crohn’s disease in the Chinese population. Journal of Cellular and Molecular Medicine. 2018 Apr;22(4):2368-77. Rank 25/133 in Medicine, Research & Experimental Science. IF = 4.302 Doi: 10.1111/jcmm.13530 (PI of bioinformatics part)
29. Xiaoxuan Xia, Haoyi Weng, Rui Sun, Ka Chun Chong, Benny Chung Ying Zee*, Maggie Haitian Wang* Incorporating methylation genome information improves prediction accuracy for drug treatment responses. BMC Genetics. 2018 Sep;19(1):78. IF = 2.569 Doi: 10.1186/s12863-018-0644-5
30. Svetlana Cherlin, Maggie Haitian Wang, Heike Bickeböller, Rita M. Cantor (2018) Detecting Responses to Treatment with Fenofibrate in Pedigrees. BMC Genetics. 2018 Sep;19(1): p64. IF = 2.569 Doi: 10.1186/s12863-018-0652-5.
31. Marc KC Chong, Benny CY Zee, Maggie H Wang (2018) Approximate Bayesian algorithm to estimate the basic reproduction number in an influenza pandemic using arrival times of imported cases. Travel Medicine and Infectious Disease. 2018 Apr 10. p80-86. Rank 14/181 in Public, Environmental & Occupational Health Science. IF = 4.45 Doi: 10.1016/j.tmaid.2018.04.004
32. Wang X, Li X, Zhang L, Wong SH, Wang MHT, Tse G, Dai RZW, Nakatsu G, Coker OO, Chen Z, Ko H, Chan JYK, Liu T, Cheng CHK, Cheng ASL, To KF, Plewczynski D, Sung JJY, Yu J, Gin T, Chan MTV, Wu WKK (2018). Oncogenes expand during evolution to withstand somatic amplification. Annals of Oncology. 2018 Sep 11. 0:1-7. Rank 9/223 in Oncology. IF = 13.93. Doi: 10.1093/annonc/mdy397
33. Lin Zhang, Wei Hu, Chi H. Cho, Francis K.L. Chan, Jun Yu, J. Ross Fitzgerald, Cynthia K.Y. Cheung, Zhangang Xiao, Jing Shen, Long F. Li, Ming X. Li, Justin C.Y. Wu, Thomas K. W. Ling, Jason Y.K. Chan, Ko Ho, Gary Tse, Siew C. Ng, Sidney Yu, Maggie H.T. Wang, Tony Gin, Hassan Ashktorab, Duane T. Smoot, Sunny H. Wong, Matthew T.V. Chan, William K.K. Wu (2018) Reduced lysosomal clearance of autophagosomes promotes survival and colonization of Helicobacter pylori. Journal of Pathology. 2018 Apr;244(4):432-44. Rank 5/79 in Pathology Science. IF= 6.253 Doi: 10.1002/path.5033
34. Rui Sun, Haoyi Weng, Xiaoxuan Xia, Ka Chun Chong, Benny Chung-Ying Zee, Maggie Haitian Wang* Gene-methylation epistasis analysis by a W-test identified enriched signals of neuronal genes in patients undergone lipid control treatment. BMC Proceedings. 2018 Sep (Vol. 12, No. 9, p. 53). IF = 0.675 Doi: 10.1186/s12919-018-0143-8
35. Hung Chan, Shan Zhao, Lin Zhang, Jeffery Ho, Czarina CH Leung, Wai T Wong, Yuanyuan Tian, Xiaodong Liu, Thomas NY Kwong, Raphael CY Chan, Sidney SB Yu, Maggie HT Wang, Gary Tse, Sunny H Wong, Matthew TV Chan, William KK Wu (2018). Clostridium difficile toxin B induces autophagic cell death in colonocytes. Journal of Cellular and Molecular Medicine. 2018 Apr;22(4):2469-77. IF = 4.302. Rank 25/133 in Medicine, Research & Experimental Science Doi: 10.1111/jcmm.13555
36. Enfu Chen; Maggie Haitian Wang; Fan He; Riyang Sun; Wei Cheng; Benny Chung Ying Zee; Steven Lau; Xiaoxiao Wang; Ka Chun Chong (2018). An increasing trend of rural infections of human influenza A (H7N9) from 2013 to 2017: A retrospective analysis of patient exposure histories in Zhejiang province, China. PloS One. 2018 Feb 15;13(2):e0193052. IF = 2.875 Doi: 10.1371/journal.pone.0193052
37. KL Hon, Yan Min Bao, Kate C. Chan, Kin Wai Chau, Rong-Shan Chen, Kun Tat Gary Cheok, Wa Keung Chiu, Li Deng, Chun-Hui He, Kin Mui Ieong, Jeng Sum C. Kung, Ping Lam, Shu Yan David Lam, Qun Ui Lee, So Lun Lee, Ting Fan Leung, Theresa N. H. Leung, Lei Shi, Ka Ka Siu, Wei-Ping Tan, Maggie Haitian Wang, Tak Wai Wong, Bao-Jing Wu, Ada Y. F. Yip, Yue-Jie Zheng & Daniel K. Ng (2018) Determinants for asthma control, quality of life and use of complementary and alternative medicine in asthmatic pediatric patients in four cities. World Journal of Pediatrics. 2018 Oct 1;14(5):482-91. IF = 1.097 Doi: 10.1007/s12519-018-0167-1
38. Steven Yuk-Fai Lau, Xiaoxiao Wang, Maggie Wang, Shelan Liu, Benny Chung-Ying Zee, Xiaoran Han, Zhao Yu, Riyang Sun, Ka Chun Chong, Enfu Chen (2018) Identification of meteorological factors associated with human infection with avian influenza A H7N9 virus in Zhejiang Province, China. Science of The Total Environment. 2018 Dec 10; 644:696-709. Rank 27/242 in Environmental Science. IF=5.89. Doi: 10.1016/j.scitotenv.2018.06.390
39. Ka Chun Chong, Pei Hu, Steven Lau, Katherine Min Jia, Wenjia Liang, Maggie Haitian Wang, Benny Chung Ying Zee, Riyang Sun, Huizhen Zheng (2018) Monitoring the age-specificity of measles transmissions during 2009-2016 in Southern China. PloS one. 2018 Oct 8;13(10): e0205339. IF = 2.875 Doi: https://doi.org/10.1371/journal.pone.0205339
40. Maggie Haitian Wang*, Haoyi Weng+, Rui Sun, Jack Lee, William Ka Kei Wu, Ka Chun Chong, Benny Chung-Ying Zee (2017) A Zoom-Focus Algorithm (ZFA) to locate the optimal testing region for rare variant association tests. Bioinformatics. 2017 Mar 11;33(15):2330-6. Rank 3/59 in Mathematics and Computational Biology. IF=5.481. Doi: 10.1093/bioinformatics/btx130
41. Maggie Haitian Wang*, Billy Chang, Rui Sun, Inchi Hu, Marc Ka Chun Chong, Benny Chung Ying Zee (2017), A Stratified Polygenic Risk Prediction Model with Application on CAGI Bipolar Disorder Sequencing Data. Human Mutation. 2017 Sep;38(9):1235-9. Rank 24/171 in Genetics & Heredity Science. IF=5.359. https://doi.org/10.1002/humu.23229
42. Roxana Daneshjou, Yanran Wang, Yana Bromberg, … Maggie Haitian Wang, …, Steve E Brenner, Alexander A Morgan (2017) Working towards precision medicine: predicting phenotypes from exomes in the Critical Assessment of Genome Interpretation (CAGI) challenges. Human Mutation. 2017 Sep;38(9):1182-92. Rank 24/171 in Genetics & Heredity Science. IF=5.359. Doi: 10.1002/humu.23229
43. Maggie Haitian Wang*, Steven YF Lau+, Chloe Kwok, Ka Chun Chong, Maria Lai, Anthony HY Chung, Chung Shun Ho, Cheuk-Chun Szeto, Benny Chung-Ying Zee (2017). Estimation of clinical parameters of chronic kidney disease (CKD) by exhaled breath full-scan mass spectrometry data and Iterative PCA with Intensity Screening (IPS) algorithm. Journal of Breath Research. 2017 Aug 21;11(3):036007. Rank 20/60 in Respiratory System Science. IF=3.489. Doi: 10.1088/1752-7163/aa7635
44. Ka Chun Chong, Chi Zhang, Benny Chung Ying Zee, Tongyong Luo, Lei Wang, Greta Chun Huen Tam, Katherine Min Jia, Riyang Sun, Maggie Haitian Wang*, Xuhua Guan (2017) Interpreting the transmissibility of measles in two different post periods of supplementary immunization activities in Hubei, China. Vaccine. 2017 Feb 15;35(7):1024-9. IF = 3.456 Doi: 10.1016/j.vaccine.2017.01.010
45. Marc Ka Chun Chong, Benny Chung Ying Zee, Maggie Haitian Wang* (2017) A statistical method utilizing information of imported cases to estimate the transmissibility for an influenza pandemic. BMC medical research methodology. 2017 Dec;17(1):31.IF =2.620 Doi: 10.1186/s12874-017-0300-1
46. Wu WKK, Li X, Wang X, Dai RZW, Cheng ASL, Wang MHT, Kwong T, Chow TC, Yu J, Chan MTV, Wong SH (2017). Oncogenes without a neighbouring tumor-suppressor gene are more prone to amplification. Molecular Biology and Evolution. 2017 Jan 12;34(4):903-7. Rank 6/171 in Genetics & Heredity Science. IF= 10.217 Doi: 10.1093/molbev/msw295
47. Qi Donga, Rutin Men, Xuelian Dan, Ying Chen, Huangcan Li, Gong Chen, Benny Zee, Maggie H.T. Wang, Ming-Liang He (2017) Hsc70 regulates the IRES activity and serves as an antiviral target of enterovirus A71 infection. Antiviral Research. 2018 Feb 28; 150:39-46. Rank 32/261 in Pharmacology & Pharmacy Science. IF=4.307. doi: 10.1016/j.antiviral.2017.11.020
48. Ruoting Men, Maoyao Wen, Mingyue Zhao, Xuelian Dan, Zongze Yang, Wenchao Wu, Maggie Haitian Wang, Xiaojing Liu, Li Yang (2017) MircoRNA-145 promotes activation of hepatic stellate cells via targeting krüppel-like factor 4. Scientific Reports. 2017 Jan 16; 7:40468. IF= 4.445 Doi: https://doi.org/10.1038/srep40468.
49. Maggie Haitian Wang*+, Rui Sun+, Junfeng Guo, Haoyi Weng, Jack Lee, Inchi Hu, Pak Sham and Benny C.Y. Zee* (2016). A fast and powerful W-test for pairwise epistasis testing. Nucleic Acids Research. 2016 Apr 25;44(12):e115-. Rank 10/293 in Biochemistry & Molecular Biology Science. IF=11.561. Doi: 10.1093/nar/gkw347
50. Rui Sun, Haoyi Weng, Inchi Hu, Junfeng Guo, William K.K. Wu, Benny Chung-Ying Zee, Maggie Haitian Wang* (2016) A W-test collapsing method for rare variant association testing in exome sequencing data. Genetic Epidemiology. 2016 Nov;40(7):591-6. IF = 2.116. DOI: 10.1002/gepi.22000.
51. Maggie Haitian Wang+, Ka Chun Chong+, Hau Yin Chung, Malina Storer, John Pickering, Zoltan Endre, Steven Lau, Chloe Kwok, Maria Lai, Benny Zee (2016). Use of a Least Absolute Shrinkage and Selection Operator (LASSO) Model to Selected Ion Flow Tube Mass Spectrometry (SIFT-MS) Analysis of Exhaled Breath to Predict the Efficacy of Dialysis. Journal of Breath Research. 2016 Sep 28;10(4):046004. Rank 20/60 in Respiratory System Science. IF=3.489. Doi: 10.1088/1752-7155/10/4/046004
52. Yaqing He, Linjie Zou, Marc Chong, Ruoting Men, Wenbo Xu, Hong Yang, Xiangjie Yao, Long Chen, Huixia Xian, Hailong Zhang, Min Luo, Jinquan Cheng, Hanwu Ma, Qianjin Feng, Yun Huang, Yujie Wang, Eng-kiong Yeoh, Benny Zee, Yuanping Zhou, Ming-Liang He and Maggie Haitian Wang* (2016) Genetic Evolution of Human Enterovirus A71 Subgenotype C4 in Shenzhen, China, 1998-2013. Journal of Infection. 2016 Jun 1;72(6):731-7. Rank 14/88 in Infectious Diseases Science. IF = 4.603. Doi: 10.1016/j.jinf.2016.03.014.
53. Chunli Wu+, Maggie Haitian Wang+, Xing Lu, Ka Chun Chong, Jason He, Chun-Yip Yau, Mark Hui, Xiaowen Cheng, Li Yang, Benny Chung-Ying Zee, Renli Zhang, and Ming-Liang He (2016) Concurrent epidemics of influenza A/H3N2 and A/H1N1pdm in Southern China: a serial cross-sectional study. Journal of Infection. 2016 Mar; 72(3):369-76. Epub 2015 Dec 30. Rank 14/88 in Infectious Diseases Science. IF = 4.603 doi: 10.1016/j.jinf.2015.12.013.
54. Ho J, Yu J, Wong SH, Zhang L, Liu X, Wong WT, Leung CCH, Choi G, Wang MH, Gin T, Chan MTV*, Wu WKK* (2016) Autophagy in sepsis: Degradation into exhaustion? Autophagy. 2016 Jul 2;12(7):1073-82. Rank 13/190 in Cell Biology Science. IF = 11.1 Doi: 10.1080/15548627.2016.1179410
55. Jeffery Ho, Lin Zhang, Xiaodong Liu, Sunny H Wong, Maggie H T Wang, Benson W M Lau, Shirley P C Ngai, Hung Chan, Gordon Choi, Czarina C H Leung, Wai T Wong, Sharon Tsang, Tony Gin, Jun Yu, Matthew T V Chan, William K K Wu. (2016) Pathological role and diagnostic value of endogenous host defence peptides in adult and neonatal sepsis: a systematic review. Shock 2017 Jun 1;47(6):673-9. IF = 3.088 Doi: 10.1097/SHK.0000000000000815.
56. Jeffery Ho, Hung Chan, Sunny H. Wong, Maggie H. T. Wang, Jun Yu, Zhangang Xiao, Xiaodong Liu, Gordon Choi, Czarina C. H. Leung, Wai T. Wong, Zheng Li, Tony Gin, Matthew T. V. Chan and William K. K. Wu (2016) The involvement of regulatory non-coding RNAs in sepsis: a systematic review. Critical Care. 2016 Dec;20(1):383. Rank 6/33 in Critical Care Medicine Science. IF=6.425. Doi: 10.1186/s13054-016-1555-3.
57. Hon KL, Kung JSC, Wang Maggie, Leung TF (2016). Clinical scores of sleep loss/pruritus and antihistamine/topical corticosteroid usage for childhood eczema. British Journal of Dermatology. 2016 Nov;175(5):1076-1078. Rank 4/64 in Dermatology Science. IF=6.129. Doi: 10.1111/bjd.14660.
58. Zhenyu Xu, Jing Shen, Maggie Haitian Wang, Tao Yi, Yangyang Yu, Yinxin Zhu, Bo Chen, Jianping Chen, Longfei Li, Minxing Li, Jian Zuo, Hui Jiang, Dexi Zhou, Jiajie Luan & Zhangang Xiao (2016) Comprehensive molecular profiling of the B7 family of immune-regulatory ligands in breast cancer. OncoImmunology. 2016 Aug 2;5(8): e1207841. Rank 31/155 in Immunology Science. IF=5.503. Doi: 10.1080/2162402X.2016.1207841.
59. Biao Zhou, Xuefen Su, Danting Su, Fangfang Zeng, Maggie Haitian Wang, Lichun Huang, Enshan Huang, Yibo Zhu, Dong Zhao, Denghua He, Xuhui Zhu, Engkiong Yeoh, Ronghua Zhang and Gangqiang Ding (2016) Dietary intake of manganese and the risk of the metabolic syndrome in a Chinese population. British Journal of Nutrition. 2016 Sep;116(5):853-63. IF = 4.139 Doi: 10.1017/S0007114516002580.
60. Rui Sun, Qiao Deng, Inchi Hu, Benny C.Y. Zee, Maggie Haitian Wang* (2016) A clustering approach to identify rare variants associated with hypertension. BMC Proc. 2016 Oct (Vol. 10, No. 7, p. 24). BioMed Central. IF = 0.887 Doi: 10.1186/s12919-016-0022-0.
61. Marc Chong, Xiaoxiao Wang, Shelan Liu, Jian Cai, Xuefen Su, Benny Chung-Ying Zee, Maggie Haitian Wang*, Enfu Chen* (2016) Interpreting the transmissibility of the avian influenza A(H7N9) infection from 2013 to 2015 in Zhejiang province, China. Epidemiology and Infection. 2016 Jun;144(8):1584-91. IF = 2.216 Doi: 10.1017/S0950268815002812.
62. Weiqin Yang, Myth T. Mok, May S. M. Li, Wei Kang, Maggie Haitian Wang, Anthony W. Chan, Jian-Liang Chou, Jie Chen, Enders K. W. Ng, Ka F. To, Jun Yu, Michael W.Y. Chan, Francis K. L. Chan, Joseph J. Y. Sung, Alfred S. L. Cheng (2016) Epigenetic silencing of GDF1 disrupts SMAD signalling to reinforce gastric cancer development. Oncogene. 2016 Apr;35(16):2133. Rank 15/171 in Genetics & Heredity Science. IF = 6.854. https://doi.org/10.1038/onc.2015.276.
63. Wei-Qin Yang, May S.M. Li, Wei Kang, Li-Han Zeng, Haitian Wang, Anthony W. Chan, Enders K.W. Ng, Ka F. To, Francis K.L. Chan, Jun Yu, Michael W.Y. Chan, Joseph J.Y. Sung, Alfred S.L. Cheng (2015). Reactivation of Growth/Differentiation Factor 1 Contributes to the Chemopreventive Effect of 5-aza-2’deoxycytidine in Gastric Cancer. Clinical Gastroenterology and Hepatology. Rank 7/80 in Gastroenterology & Hepatology Science. IF=7.683. Doi: 10.1158/1538-7445.AM2014-1245
64. Bin Jiao, Xiaoyan Liu, Lin Zhou, Maggie Haitian Wang, Yafang Zhou, Tingting Xiao, Weiwei Zhang, Rui Sun, Mary Miu Yee WAYE, Beisha Tang, Lu Shen (2015) Polygenic Analysis of Late-onset Alzheimer Disease From Mainland China. PLoS ONE. 2015 Dec 17;10(12): e0144898. IF = 3.504. doi: 10.1371/journal.pone.0144898.
65. Maggie Haitian Wang, Kelvin Tsoi, Xin Lai, Marc Chong, Tian Zheng, Shaw-Hwa Lo, Benny Zee and Inchi Hu (2015). Two screening methods for genetic association study with application on psoriasis microarray data sets. IEEE International Congress on Big Data. 2015 Jun 27 (pp. 324-326). Doi: 10.1109/BigDataCongress.2015.55.
66. Marc Chong, Kelvin Tsoi, Maggie Haitian Wang, Benny Zee, Fung Hong, EK Yeoh, Eliza Wong, Carrie Yam, Patsy Chau, Colin Graham (2015). Using a System Dynamic Model to Evaluate the Patient Flow in an Emergency Department of Hong Kong. 2015 IEEE International Congress on Big Data. IEEE, 2015. p. 320-323. Doi: 10.1109/BigDataCongress.2015.54.
67. Xin Lai, Liu Liu, Paul B.S. Lai, Kelvin Tsoi, Maggie Haitian Wang, Ka Chun Chong and Benny Zee. Risk-adjusted Monitoring Method for Surgical Data Methodology for Data Analytics (Work in Progress) 2015 IEEE International Congress on Big Data. IEEE, 2015. p. 317-319. Doi: 10.1109/BigDataCongress.2015.53.
68. Ka Chun Chong, William Goggins, Benny Chung Ying Zee, Maggie Haitian Wang (2015) Identify Meteorological Drivers for the Seasonal Variations of Influenza Infections in a Subtropical City, Hong Kong. International Journal of Environmental Research and Public Health. 2015 Jan 28;12(2):1560-76. ijerph-69059; IF = 2.499. doi: 10.3390/ijerph120201560.
69. Jin Shen, William K.K. Wu, Maggie H. Wang, Ka F. To, Yangchao Chen, Zhangang Xiao, May S.M. Li, Joanna H. Tong, Wei Kang, Lin Zhang, Lin Wang, Lan Lu, Ruby L.Y. Chan, Jun Yu, Francis K.L. Chan, Joseph J.Y. Sung, Alfred S.L. Cheng, Chi H. Cho (2014) Epigenetic silencing of miR-490-3p reactivates the chromatin remodeler SMARCD1 to promote Helicobacter pylori-induced gastric carcinogenesis. Cancer Research. 2015 Feb 15;75(4):754-65. Rank 17/223 in Oncology Science. IF=9.13. Doi: 10.1158/0008-5472.CAN-14-1301.
70. Maggie Haitian Wang, Jiexin Li, Venus Yeung, Benny Zee, Mary Waye, Suzanne Ho (2014) Four pairs of gene-gene interactions associated with increased risk for type 2 diabetes (CDKN2BAS-KCNJ11), obesity (SLC2A9-IGF2BP2, FTO-APOA5), and hypertension (MC4R-IGF2BP2) in Chinese women. Meta Gene. IF = 1.129. Doi:10.1016/j.mgene.2014.04.010.
71. Lai He+, Jin Zhao+, Maggie Haitian Wang+, Kenny KY Siu, Yong-Xia Gan, Lin Chen, Albert WN Leung, Hsiang-Fu Kung, Benny Zee, Zheng-Rong Yang, Ming-Liang He (2014) Interleukin-27 (IL-27) differentially associated with HIV viral load and CD4+ in HIV monoinfected and HIV/HCV coinfected groups. PLoS ONE. 2014 May 9;9(5): e96792. IF = 3.769 Doi: 10.1371/journal.pone.0096792.
72. XIE Chen; WANG Zhijun; WANG Charles; XU Jun; WEN Zhining; WANG Haitian; SHI Leming; CHOW S.s. Moses; HUANG Ying and ZUO Zhong. (2013) Utilization of Gene Expression Signature for Quality Control of Traditional Chinese Medicine Formula Si-Wu-Tang. The AAPS Journal. 2013 Jul 1;15(3):884-92. IF = 4.374 Doi: 10.1208/s12248-013-9491-5.
73. Chun-Li Wu+, Juan Lu+, Maggie Haitian Wang+, Xing Lv, Ying Chen, Xin Wang, Hsiang-fu Kung, Benny Zee, Xiao-wen Cheng, Ming-Liang He (2013) Cross-sectional survey of influenza antibodies before and during the 2009 pandemic in Shenzhen, China. PLoS ONE. 2013 Jan 29;8(1): e53847. IF= 4.050 doi: 10.1371/journal.pone.0053847.
74. Maggie Haitian Wang, Shaw-Hwa Lo, Tian Zheng and Inchi Hu (2012) Interaction-based feature selection and classification for high-dimensional biological data. Bioinformatics. 2012 Sep 3;28(21):2834-42. Rank 3/59 in Mathematics and Computational Biology. IF=5.481. Doi: 10.1093/bioinformatics/bts531.
CONFERENCE JOURNAL PROCEEDINGS OR SUPPLEMENTS (peer-reviewed full paper)
75. Maggie Haitian Wang, Chien-Hsun Huang, Tian Zheng, Shaw-Hwa Lo and Inchi Hu (2014) Discovering pure gene-environment interactions in blood pressure genome-wide association studies data: a two-step approach incorporating new statistics. BMC Proceedings. 2014 Jun (Vol. 8, No. 1, p. S62). BioMed Central. IF = 0.931 Doi: 10.1186/1753-6561-8-S1-S62.
76. Michael Agne, Chien-Hsun Huang, Inchi Hu, Maggie Haitian Wang, Tian Zheng, and Shaw-Hwa Lo (2014) Considering Interactive Effects in the Identification of Influential Regions with Extremely Rare Variants via Fixed Bin Approach. BMC Proceedings. 2014 Jun (Vol. 8, No. 1, p. S7). BioMed Central. IF = 0.931 Doi: 10.1186/1753-6561-8-S1-S7.
77. Ruixue Fan, Chien-Hsun Huang, Inchi Hu, Maggie Haitian Wang, Tian Zheng and Shaw-Hwa Lo (2014) A Partition-based Approach to Identify Gene-Environment interactions in Genome-Wide Association Studies. BMC Proceedings. 2014 Jun (Vol. 8, No. 1, p. S60). BioMed Central. IF = 0.931 Doi: 10.1186/1753-6561-8-S1-S60.
78. Nathan Tintle, Hugues Aschard, Inchi Hu, Nora Nock, Haitian Wang and Elizabeth Pugh (2011) Inflated Type I Error Using Aggregation Methods for Rare Variant Data. Genetic Epidemiology. 2011;35(S1): S56-60. IF = 1.188 Doi: 10.1002/gepi.20650.
79. Haitian Wang, Chien-Hsun Huang, Tian Zheng, Shaw-Hwa Lo and Inchi Hu (2011) New Insights on Old Methods in Identifying Causal Rare Variants, BMC Proceedings. 2011 Dec (Vol. 5, No. 9, p. S50). BioMed Central. IF = 1.188 Doi: 10.1186/1753-6561-5-S9-S50.
80. Michael Agne, Chien-Hsun Huang, Inchi Hu, Haitian Wang, Tian Zheng and Shaw-Hwa Lo (2011) Identifying influential regions in extremely rare variants using a fixed-bin approach, BMC Proceedings. 2011 Dec (Vol. 5, No. 9, p. S3). BioMed Central. IF = 1.188 Doi: 10.1186/1753-6561-5-S9-S3.
Professional Services
06/2018 – Current Reviews Editor of Human Genetics, Springer (IF 5.2, Q1 in Genetics & Heredity)
2019 – Current Scientific Program Committee, International Genetic Epidemiology Society (IGES)
2018 – Current Bioinformatics Society of Macau, Councilmember
2017 – Current Communication Committee, International Genetic Epidemiology Society (IGES)