CUHK_CCT00103
2006-04-12
Retrospective
Soley funded by the Department of Anaesthesia and Intensive Care, CUHK
Not applicable
Not applicable
Prof. Manoj K Karmakar
Associate Professor, Department of Anaesthesia and Intensive Care, CUHK, Hong Kong
E-mail: karmakar@cuhk.edu.hk
Prof. Manoj K Karmakar
Associate Professor, Department of Anaesthesia and Intensive Care, CUHK, Hong Kong
E-mail: karmakar@cuhk.edu.hk
Prospective randomized evaluation of the benefits of combining thoracic paravertebral block with general anesthesia in patients undergoing major breast cancer surgery.
Single-shot Thoracic paravertebral injection and breast surgery
Yes
2000-12-15
Pain, respiratory function, incidence of nausea and vomiting after breast surgery
Other
Thoracic paravertebral Injection
Single-shot thoracic paravertebral block in conjunction with general anaesthesia
Single (pre-incision) injection
Only standardaized General anaesthesia with no paraverterbal injection
Inclusion: All consenting adult ASA 1-3 patients under the age of 75 years undergoing major breast cancer surgery will be recruited for this study. Exclusion: The following patients will be excluded from the study: 1. Patients with a known allergy to local anaesthetic drugs. 2. Patient with infection at the site of block placement. 3. Patient with a bleeding tendency or with evidence of coagulopathy. 4. Patient with pre-existing neurological or muscular disorders. 5. Patient with history of psychiatric illness. 6. Pregnant patients. 7. Patients with pre-existing nausea or vomiting. 8. Patients who in the 24 h before surgery received opioids or drugs with antiemetic properties.
Randomized
Active
Single-blind
Parallel
2001-01-01
90
Complete
Postoperative nausea and vomiting
Postoperative pain, spirometry (FVC, FEV1 and PEFR)
2006-04-12
Yes
None
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