CUHK_CCT00103
2006-04-12
Retrospective
Soley funded by the Department of Anaesthesia and Intensive Care, CUHK
Not applicable
Not applicable
Prof. Manoj K Karmakar
E-mail: karmakar@cuhk.edu.hk
Associate Professor, Department of Anaesthesia and Intensive Care, CUHK, Hong Kong
Prof. Manoj K Karmakar
E-mail: karmakar@cuhk.edu.hk
Associate Professor, Department of Anaesthesia and Intensive Care, CUHK, Hong Kong
Prospective randomized evaluation of the benefits of combining thoracic paravertebral block with general anesthesia in patients undergoing major breast cancer surgery.
Single-shot Thoracic paravertebral injection and breast surgery
Yes
2000-12-15
Pain, respiratory function, incidence of nausea and vomiting after breast surgery
Other
Thoracic paravertebral Injection
Single-shot thoracic paravertebral block in conjunction with general anaesthesia
Single (pre-incision) injection
Only standardaized General anaesthesia with no paraverterbal injection
Inclusion: All consenting adult ASA 1-3 patients under the age of 75 years undergoing major breast cancer surgery will be recruited for this study.
Exclusion: The following patients will be excluded from the study: 1. Patients with a known allergy to local anaesthetic drugs. 2. Patient with infection at the site of block placement. 3. Patient with a bleeding tendency or with evidence of coagulopathy. 4. Patient with pre-existing neurological or muscular disorders. 5. Patient with history of psychiatric illness. 6. Pregnant patients. 7. Patients with pre-existing nausea or vomiting. 8. Patients who in the 24 h before surgery received opioids or drugs with antiemetic properties.
Randomized
Active
Single-blind
Parallel
2001-01-01
90
Complete
Postoperative nausea and vomiting
Postoperative pain, spirometry (FVC, FEV1 and PEFR)
2006-04-12
ChiCTR-TRC-06000687
2010-05-04
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