CUHK_CCT00100
2006-04-12
Retrospective
not applicable
RGC Grant CUHK4406/05M Project Code 2140452
RGC
Department of Anaesthesia and Intensive Care
Manoj K Karmakar
Department of Anaesthesiaand Inteneive Care, CUHK
+85226321311
karmakar@cuhk.edu.hk
Department of Anaesthesia and Intensive Care, The Chinese University of Hong Kong, Prince of Wales Hospital
Manoj K Karmakar
Department of Anaesthesia and Intensive Care, CUHK
+85226321311
karmakar@cuhk.edu.hk
Department of Anaesthesia and Intensive Care, The Chinese University of Hong Kong, Prince of Wales Hospital
Continuous Thoracic Paravertebral Block: Effects on Acute and Chronic Pain, and Quality of Life after Breast Cancer Surgery.
COntinuous Thoracic Paravertebral Block for Breast surgery and Quality of Life
Thoracic paravertebral block and chronic pain after breast surgery
Hong Kong
Yes
2004-12-14
nil
Other
Thoracic paravertebral block
Thoracic paravertebral block
3 days
Control placebo paravertebral infusion
Inclusion: Consenting adult ASA 1-3 patients under the age of 70 years undergoing major breast cancer surgery (which includes axillary lymph node dissection) will be recruited for this study.
Exclusion: The following patients will be excluded from the study: history of chronic pain, history of regular analgesic usage, contraindication to the use of non-steroidal anti-inflammatory drugs (NSAID), known allergy to local anaesthetic drugs, infection at the site of block placement, bleeding tendency or with evidence of coagulopathy, pre-existing neurological or muscular disorders, history of psychiatric illness, pregnant patients, pre-existing nausea or vomiting, patients who in the 24 h before surgery received opioid or drugs with antiemetic properties, patients who received chemotherapy or radiotherapy before surgery and patients with breast pain before surgery.
18
70
Female
Interventional
Randomized
Placebo
Double-blind
Parallel
2005-09-01
180
Complete
Incidence of chronic pain after breast surgery
Quality of life
2011-12-12
ChiCTR-TRC-09000684
2010-05-04
Yes
not applicable
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