CUHK_CCT00100
2006-04-12
Retrospective
not applicable
Departmental
Department of Anaesthesia and Intensive Care
None
Manoj K Karmakar
Department of Anaesthesiaand Inteneive Care, CUHK
+85226321311
karmakar@cuhk.edu.hk
Department of Anaesthesia and Intensive Care, The Chinese University of Hong Kong, Prince of Wales Hospital
Manoj K Karmakar
Department of Anaesthesia and Intensive Care, CUHK
+85226321311
karmakar@cuhk.edu.hk
Department of Anaesthesia and Intensive Care, The Chinese University of Hong Kong, Prince of Wales Hospital
Continuous Thoracic Paravertebral Block: Effects on Acute and Chronic Pain and Quality of Life after Breast Cancer Surgery.
Continuous Thoracic Paravertebral Block: Effects on Acute and Chronic Pain and Quality of Life after Breast Cancer Surgery - A 5 year follow up.
Effects of Thoracic paravertebral block on acute and chronic pain after breast surgery
Hong Kong
Yes
2004-12-14
Chronic Pain and Quality of Breast Cancer Surgery
Other
Thoracic paravertebral block before surgery, postoperative follow up, telephone interview
Thoracic paravertebral block done before surgery, postoperative 3 days ward follow-up, 1 and 3 months telephone interview for acute pain data. Telephone interview once per year for 5 years for the incidence of chronic pain condition and quality of life after surgery.
5 years follow up after date of surgery
Patients are randomized into 3 groups: Control group, placebo paravertebral infusion group, Ropivacaine paravertebral infusion group
Inclusion: Consenting adult ASA 1-3 patients under the age of 70 years undergoing major breast cancer surgery (which includes axillary lymph node dissection) will be recruited for this study.
Exclusion: The following patients will be excluded from the study: history of chronic pain, history of regular analgesic usage, contraindication to the use of non-steroidal anti-inflammatory drugs (NSAID), known allergy to local anaesthetic drugs, infection at the site of block placement, bleeding tendency or with evidence of coagulopathy, pre-existing neurological or muscular disorders, history of psychiatric illness, pregnant patients, pre-existing nausea or vomiting, patients who in the 24 h before surgery received opioid or drugs with antiemetic properties, patients who received chemotherapy or radiotherapy before surgery and patients with breast pain before surgery.
18
70
Female
Interventional
Randomized
Placebo
Double-blind
Parallel
2005-04-01
180
Complete
Data collection on aucte pain and quality of life at 1 and 3 months after surgery are finished.
Data collection of the incidence of chronic pain and quality of life after breast surgery over 5 years are in progress.
Quality of life 5 years after surgery
2011-12-12
ChiCTR-TRC-06000684
2010-05-04
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