CUHK_CCT00100
2006-04-12
Retrospective
RGC Grant CUHK4406/05M Project Code 2140452
RGC
Department of Anaesthesia and Intensive Care
Manoj K Karmakar
Department of Anaesthesiaand Inteneive Care, CUHK
karmakar@cuhk.edu.hk
Manoj K Karmakar
Department of Anaesthesia and Intensive Care, CUHK
karmakar@cuhk.edu.hk
Continuous Thoracic Paravertebral Block: Effects on Acute and Chronic Pain, and Quality of Life after Breast Cancer Surgery.
Thoracic paravertebral block and chronic pain after breast surgery
Yes
2004-12-14
nil
Other
Thoracic paravertebral block
Thoracic paravertebral block
3 days
Control placebo paravertebral infusion
Inclusion: Consenting adult ASA 1-3 patients under the age of 70 years undergoing major breast cancer surgery (which includes axillary lymph node dissection) will be recruited for this study. Exclusion: The following patients will be excluded from the study: history of chronic pain, history of regular analgesic usage, contraindication to the use of non-steroidal anti-inflammatory drugs (NSAID), known allergy to local anaesthetic drugs, infection at the site of block placement, bleeding tendency or with evidence of coagulopathy, pre-existing neurological or muscular disorders, history of psychiatric illness, pregnant patients, pre-existing nausea or vomiting, patients who in the 24 h before surgery received opioid or drugs with antiemetic properties, patients who received chemotherapy or radiotherapy before surgery and patients with breast pain before surgery.
Randomized
Placebo
Double-blind
Parallel
2005-09-01
180
Recruiting
Incidence of chronic pain after breast surgery
Quality of life
2011-12-12
Yes
None
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