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Trial History Detail on 2006-01-27

CUHK_CCT00096

2006-01-27

Prospective

Departmental

None

Matthew Chan

Department ofAnaesthesia and Intensive Care

mtvchan@cuhk.edu.hk

Matthew Chan

Department ofAnaesthesia and Intensive Care

mtvchan@cuhk.edu.hk

Combination of Aprepitant and Dexamethasone to Prevent Postoperative Nausea and Vomiting

Yes

2005-11-01

Anesthesia

Drug

Aprepitant

Immediately before induction of anesthesia

Dexamethasone and a combination of Aprepitant and Dexamethasone

Inclusion criteria: All women (age 18-65 years) undergoing open gynecologic surgery will be eligible Exclusion criteria: (1) Patients had preexisting nausea or vomiting (2) Patients had received opioids or drugs with known antiemetic properties in the 24 hours before surgery. (3) Pregnant patients (4) Patients with history of esophageal reflux, opioid or alcohol abuse.

Randomized

Placebo

Double-blind

Factorial

2006-02-01

320

Recruiting

Complete response (no vomiting, no nausea, no rescue antiemetic)

QoR,FLIE questionnaire, Pain and nausea score

No

2009-11-27


Yes

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