CUHK_CCT00091
2005-11-16
Prospective
Departmental
Department of Anaesthesia and Intensive Care, The Chinese University of Hong Kong
Matthew Chan
Department of Anaesthesia and Intensive Care, The Chinese University of Hong Kong
mtvchan@cuhk.edu.hk
Matthew Chan
Department of Anaesthesia and Intensive Care, The Chinese University of Hong Kong
mtvchan@cuhk.edu.hk
Second Generation Antihistamine to Prevent Postoperative Nausea and Vomiting
Yes
2005-11-01
Postoperative nausea and vomiting
Drug
Cetirizine
Single dose, given one hour preoperatively
Dexamethasone and placebo
All women undergoing laparoscopic gynecologic surgery will be eligible if they: (1) are aged between 18 and 60 years; (2) are American Society of Anesthesiologists physical status 1-2;
Exclusion criteria: (1) Patients with preexisting nausea or vomiting (2) Patients who had received opioids or drugs with known antiemetic properties in the 24 hours before surgery. (3) Pregnant patients
Randomized
Placebo
Double-blind
Parallel
2005-12-01
390
Complete
Complete treatment response (i.e. no nausea, no vomiting, no need for rescue antiemetic)
Patient satisfaction and quality of recovery
2009-11-27
Yes
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