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Trial Detail

CUHK_CCT00091

2005-11-16

Prospective

NA

Departmental

Department of Anaesthesia and Intensive Care, The Chinese University of Hong Kong

NA

Matthew Chan

Department of Anaesthesia and Intensive Care, The Chinese University of Hong Kong

26322736

mtvchan@cuhk.edu.hk

The Chinese University of Hong Kong

Matthew Chan

Department of Anaesthesia and Intensive Care, The Chinese University of Hong Kong

26322736

mtvchan@cuhk.edu.hk

The Chinese University of Hong Kong

Second Generation Antihistamine to Prevent Postoperative Nausea and Vomiting

NA

NA

Hong Kong

Yes

2005-11-01

Postoperative nausea and vomiting

Drug

Cetirizine

Single dose, given one hour preoperatively

Dexamethasone and placebo

All women undergoing laparoscopic gynecologic surgery will be eligible if they: (1) are aged between 18 and 60 years; (2) are American Society of Anesthesiologists physical status 1-2;

Exclusion criteria: (1) Patients with preexisting nausea or vomiting (2) Patients who had received opioids or drugs with known antiemetic properties in the 24 hours before surgery. (3) Pregnant patients

18

60

Both Male and Female

Interventional

Randomized

Placebo

Double-blind

Parallel

2005-12-01

390

Complete

Complete treatment response (i.e. no nausea, no vomiting, no need for rescue antiemetic)

Patient satisfaction and quality of recovery

No

2009-11-27

ChiCTR-TRC-09000672

2010-05-04

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