CUHK_CCRB00580
2018-01-17
Prospective
2017.013
Nil
Nil
Nil
Not Applicable
Cheung Wing Ching
1F, 1 floor, EF Block (Special Block), Department of OG, Prince of Wales Hospital, Shatin
3505 1764
cosycheung@cuhk.edu.hk
Department of OG
Hong Kong
YIU LEUNG CHAN
1F, 1 floor, EF Block (Special Block), Department of OG, Prince of Wales Hospital, Shatin
3505 3199
cylcps@yahoo.com.hk
Obstetric and gynaecology, CUHK
Hong Kong
A study on the relation between semen quality, compositions and microflora in male HBV carriers
A study on the relation between semen quality, compositions and microflora in male HBV carriers
男性乙型肝炎攜帶者的精液質量、組合物和微生物群落之間的關係
Hong Kong
Yes
2017-03-14
Joint CUHK-NTEC Clinical Research Ethics Committee
2017.013
Hepatitis B virus (HBV) carrier
semen quality
semen composition
semen microflora
Other
semen analysis, blood taking and filling in questionnaires
1. provide a semen sample (A portion of semen will be taken for routine analysis, rest of the sample is for research purposes).
2. take 5 – 10ml blood sample for hormonal test or other biochemical molecules (such as enzyme or amino acid). Blood taking may cause minimal pain and very minimal risk of infection.
3. Spend 5 – 10 minutes to fill in the questionnaire.
Nil
Nil
Nil
Nil
Nil
Nil
Nil
Nil
Nil
Chinese male
HBV carrier
40 non HBV carriers will also be recruited as a group of control.
genetic defects (Phenotypically abnormal)
azoospermia
18
60
Male
Observational
Not Applicable
Not Applicable
Not Applicable
Not Applicable
Other
This is not a drug trial
2018-01-23
307 HBV carrier & 40 healthy non HBV patients: totally 347
Recruiting
To find out what is/are the major factor/s impair male fertility in chronical HBV carriers.
semen sampling, blood sampling and filling in a questionnaire about lifestyle
(1) at the day of semen analysis, (2) follow up for fertility outcome
Possibly minimize the viral infection/transmission outcome and maximize subfertility treatment outcome among male HBV carriers
semen sampling, blood sampling and filling in a questionnaire about lifestyle
(1) at the day of semen analysis, (2) follow up for fertility outcome
2020-07-06
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