CUHK_CCT00051
2005-09-09
Retrospective
Takeda Chemical Industries, LTD
Department of Medicine & Therapeutics, The Chinese University of Hong Kong
N/A
Leata Chan
Department of Medicine & Therapeutics, The Chinese University of Hong Kong
leata@chuk.edu.hk
Prof. John E. Sanderson
Professor of Cardiology, Keele University Medical School
ohn.Sanderson@uhns.nhs.uk
The effect of angiotensin receptor blockade alone or in combination with spironolactone on the process of ventricular remodeling in chronic heart failure.
Yes
2001-07-03
Heart and Blood Vessel Diseases
Drug
Heart Failure Patients
one year
Candesartan + Spirolactone verus Candesartan + Placebo
Inclusion criteria *Typical features of congestive heart failure. *LVEF < 40%. Exclusion criteria *Patients with renal failure, serum creatinine > 200 mmol/ltr. *Other major serious medical conditions such as malignancy, liver failure, uncontrolled diabetes. Gender and age will be balanced in the two randomized groups.
Randomized
Placebo
Double-blind
Parallel
2001-10-08
50
Complete
We sought to determine the beneficial effect of candesartan alone or in combination with spironolactone on left ventricular remodelling
N/A
2009-12-28
Yes
None
|
|
|
|
|
---|---|---|---|---|
No documents yet. |