W-test: dataset adaptive association test for main and interaction
effects in GWAS data |
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Guide - C++ - Linux |
Simulation study of main effect testing
using W-test (k=2) A. Simulation model of main effect: The genotype matrix is composed of 1,000
SNPs and 1,000 subjects. The phenotype is determined by setting Y equal to X1
or X2 at 20% probability, and Y has 60% probability of being a
random 0 and 1. The genotype takes binary values under a dominant genetic
model assumption. B. Results of
simulation study:
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Copyright |
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