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Application: To calculate
the sample sizes needed to detect a relevant simple correlation with specified
significance level and power, following hypotheses are usually used:
Procedure:
a) value of α, the probability of type I error
b) value of β, the probability of type II error, or (1-power) of the test
c) value of r, the sample correlation based on N observations
Formula:
To employ Fisher’s arctanh
transformation:
Given a sample correlation r based on N observations
that is distributed about an actual correlation value (parameter) ρ, thenis normally distributed with mean
and variance
.
Under the null hypothesis, the test statistic iswhere
The sample size to achieve specified significance level and
power is
whereis the upper 100(1-p) percentile of the standard normal distribution.
Notations:
α: The
probability of type I error (significance level) is the probability of rejecting the true null
hypothesis.
β: The
probability of type II error (1 – power of the test) is the probability of
not rejecting the false null hypothesis.
Example:
Suppose one wishes to detect a simple corrleation r (r=0.4) of N observations. Using a two sided test, 5% significance level test (α=0.05) with power 80% power (β=0.2), the required sample size is approximate 47 (n=47).
Reference: Lachin (1981) Controlled Clinical Trials 2: 93-113