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Trial History Detail on 2009-11-19

CUHK_CCT00141

2007-09-12

Retrospective

CoDA Study

RGC

RGC

NA

Matthew Chan

Department of Anaesthesia and Intensive Care

mtvchan@cuhk.edu.hk

Matthew Chan

Department of Anaesthesia and Intensive Care

mtvchan@cuhk.edu.hk

Cognitive Dysfunction after Anesthesia (CoDA) Study

CoDA Study

Yes

2003-10-07

Anesthesia

Drug

Neurophysiology guided Anaesthesia

Intraoperative period

Routine care

Inclusion criteria: (1) Patients aged ≥ 60 years with an American Society of Anesthesiologists physical status of between 1 and 4 who have been scheduled for elective non-cardiac surgery. (2) Surgery expected to last for 2 hours or longer with an anticipated hospital stay of at least 4 days.

Exclusion criteria: (1) Patients not expected to be available for, or cooperate with, perioperative interviews. (2) Patients with major psychosis who are taking tranquillizers or antidepressants (3) Patients with disease of the central nervous system, including known or suspected dementia or memory impairment (defined as a Mini-Mental State Examination score of ≤ 23). (4) Patients with illiteracy, significant hearing or visual impairment, or language difficulties will also be excluded.

Randomized

Placebo

Double-blind

Parallel

2005-01-01

1,000

Recruiting

Cognitive function using neuropsychologic tests

(1) Recovery time (2) Quality of recovery (3) Major perioperative complications

No

2019-09-04


Yes

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