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Trial Detail

CUHK_CCT00016

2005-09-05

Retrospective

none

Chinese University of Hong Kong Institute of Chinese Medicine; Chinese University of Hong Kong; and BUPA Foundation

The Chinese University of Hong Kong

Kwong Wah Hospital

Fion Yip

Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Shatin, Hong Kong

Tel or Tel [852] 26323593

email or Email fionyip@cuhk.edu.hk

Department of Medicine and Therapeutics, The Chinese University of Hong Kong

Larry Baum

School of Pharmacy, The Chinese University of Hong Kong, Shatin, Hong Kong

Tel or Tel [852] 26323146

email or Email lwbaum@cuhk.edu.hk

School of Pharmacy, The Chinese University of Hong Kong

A Pilot Study of Curcumin and Ginkgo for Treating Alzheimer's Disease

Six-month randomized, placebo-controlled, double-blind, pilot clinical trial of curcumin in patients with Alzheimer disease

Curcumin for AD

Hong Kong

Yes

2003-04-23

Nervous System Diseases

Drug

Curcumin and ginkgo extract

6 months

Placebo

Inclusion: Possible or probable AD.

Exclusion: Anticoagulant or antiplatelet treatment or bleeding risk factors; currently smoking; or other severe illness.

50

none

Both Male and Female

Interventional

Randomized

Placebo

Double-blind

Parallel

2004-10-07

30

Complete

Setting up formulation, patient recruitment, and assay procedures at 0, 1, and 6 months, in preparation for a later clinical trial testing the effectiveness of curcumin and ginkgo in slowing AD progression.

Change in biochemical measures of AD: Plasma isoprostane and A-beta levels at 1 and 6 months. Change in cognitive measures of AD: MMSE at 6 months. Change in others: cholesterol, lipid, C reactive protein, and metal levels in serum at 1 and 6 months. Curcumin and metabolites at 1 month.

No

2011-03-02

ChiCTR-TRC-09000626

2010-05-04

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