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Trial Detail

CUHK_CCRB00623

2018-09-05

Prospective

Joint CUHK-NTEC Clinical Research Ethics Committee 2018.287

None

Department of Anaesthesia and Intensive Care, The Chinese University of Hong Kong

N/A

Not Applicable

Lowell Ling

4/F Main Clinical Block and Trauma Centre,
Prince of Wales Hospital, Shatin,
New Territories, Hong Kong

3505 2735

lowell.ling@cuhk.edu.hk

Department of Anaesthesia and Intensive Care, The Chinese University of Hong Kong

Hong Kong

Lowell Ling

4/F Main Clinical Block and Trauma Centre,
Prince of Wales Hospital, Shatin,
New Territories, Hong Kong

3505 2735

lowell.ling@cuhk.edu.hk

Department of Anaesthesia and Intensive Care, The Chinese University of Hong Kong

Hong Kong

Genome wide expression in infection and sepsis: a pilot propsective cohort study

Genome wide expression in infection and sepsis: a pilot propsective cohort study

感染和膿毒症基因組廣泛表達:先導研究

Hong Kong

Yes

2018-07-21

Joint CUHK-NTEC Clinical Research Ethics Committee

2018.287

sepsis

Other

This is not an intervention trial.

This is not an intervention trial.

This is not an intervention trial.

This is not an intervention trial.

This is not an intervention trial.

This is not an intervention trial.

This is not an intervention trial.

This is not an intervention trial.

This is not an intervention trial.

This is not an intervention trial.

This is not an intervention trial.

adult patients with susepcted communiy accquired pneumonia

immunosupression

current malignancy

chest symptoms not solely accounted by pneumonia (cardiac failure, non-cardiogenic pulmonary oedema, suspected pulmonary embolism, suspected secondary acute respiratory distress syndrome)

prisoner/cognitive impairment/age less than 18

hospitalization within 1 month

whole blood transfusion within 1 month

blood samples for gene expression could not be taken within 24 hours of admission

18

99

Both Male and Female

Observational

Not Applicable

Not Applicable

Not Applicable

Not Applicable

Other

N/A

Feasibility of a genome wide expression study on patients with pneumonia with respect to recruitment, data collection and gene expression analysis

2018-10-01

10-20

Complete

feasibility of a genome wide expression study on patients with pneumonia

recruitment rate, gene expression analysis

admission to hospital

peripheral blood mononuclear cell genome wide expression differences uncomplicated pneumonia versus pneumonia with associated sepsis

association of gene expression pattern and frequency of disease

admission to hospital

peripheral blood mononuclear cell genome wide expression and association with organ dysfunction

association of gene expression pattern and sequential organ failure assessment score

admission to hospital

peripheral blood mononuclear cell genome wide expression and association with clnical outcomes

association of gene expression pattern and clinical outcomes such as mortality, hospital length of stay

admission to hospital

No

2019-12-06

ChiCTR1800018535

2018-09-05

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