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Trial History Detail on 2011-04-01

CUHK_CCT00090

2005-11-16

Prospective

None

Departmental

Department of Anaesthesia and Intensive Care, The Chinese University of Hong Kong

None

Matthew Chan

Department of Anaesthesia and Intensive Care, The Chinese University of Hong Kong

26322736

mtvchan@cuhk.edu.hk

The Chinese University of Hong Kong

Matthew Chan

Department of Anaesthesia and Intensive Care, The Chinese University of Hong Kong

26322736

mtvchan@cuhk.edu.hk

The Chinese University of Hong Kong

Single dose Aprepitant to Prevent Postoperative Nausea and Vomiting

NA

NA

Hong Kong

Yes

2005-11-01

Postoperative nausea and vomiting

Drug

Aprepitant

Preoperative single dose

Placebo

All women undergoing open gynecologic surgery will be eligible if they: (1) are aged between 18 and 60 years; (2) are American Society of Anesthesiologists physical status 1-2;

Exclusion criteria: (1) Patients had preexisting nausea or vomiting (2) Patients had received opioids or drugs with known antiemetic properties in the 24 hours before surgery. (3) Pregnant patients.

18

60

Both Male and Female

Interventional

Randomized

Placebo

Double-blind

Parallel

2005-12-01

320

Unknown

Complete treatment response (i.e. no vomiting, no nausea and no need for rescue antiemetics)

Patient satisfaction and quality of reciovery

No

2011-11-25

ChiCTR-TRC-09000671

2010-05-04


Yes

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