CUHK_CCT00090
2005-11-16
Prospective
Departmental
Department of Anaesthesia and Intensive Care, The Chinese University of Hong Kong
Matthew Chan
Department of Anaesthesia and Intensive Care, The Chinese University of Hong Kong
mtvchan@cuhk.edu.hk
Matthew Chan
Department of Anaesthesia and Intensive Care, The Chinese University of Hong Kong
mtvchan@cuhk.edu.hk
Single dose Aprepitant to Prevent Postoperative Nausea and Vomiting
Yes
2005-11-01
Postoperative nausea and vomiting
Drug
Aprepitant
Preoperative single dose
Placebo
All women undergoing open gynecologic surgery will be eligible if they: (1) are aged between 18 and 60 years; (2) are American Society of Anesthesiologists physical status 1-2;
Exclusion criteria: (1) Patients had preexisting nausea or vomiting (2) Patients had received opioids or drugs with known antiemetic properties in the 24 hours before surgery. (3) Pregnant patients.
Randomized
Placebo
Double-blind
Parallel
2005-12-01
320
Recruiting
Complete treatment response (i.e. no vomiting, no nausea and no need for rescue antiemetics)
Patient satisfaction and quality of reciovery
2011-11-25
Yes
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