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Trial History Detail on 2007-09-15

CUHK_CCT00090

2005-11-16

Prospective

Departmental

Department of Anaesthesia and Intensive Care, The Chinese University of Hong Kong

Matthew Chan

Department of Anaesthesia and Intensive Care, The Chinese University of Hong Kong

mtvchan@cuhk.edu.hk

Matthew Chan

Department of Anaesthesia and Intensive Care, The Chinese University of Hong Kong

mtvchan@cuhk.edu.hk

Single dose Aprepitant to Prevent Postoperative Nausea and Vomiting

Yes

2005-11-01

Postoperative nausea and vomiting

Drug

Aprepitant

Preoperative single dose

Placebo

All women undergoing open gynecologic surgery will be eligible if they: (1) are aged between 18 and 60 years; (2) are American Society of Anesthesiologists physical status 1-2; Exclusion criteria: (1) Patients had preexisting nausea or vomiting (2) Patients had received opioids or drugs with known antiemetic properties in the 24 hours before surgery. (3) Pregnant patients.

Randomized

Placebo

Double-blind

Parallel

2005-12-01

320

Recruiting

Complete treatment response (i.e. no vomiting, no nausea and no need for rescue antiemetics)

Patient satisfaction and quality of reciovery

No

2011-11-25


Yes

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