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Trial History Detail on 2018-01-17

CUHK_CCRB00580

2018-01-17

Prospective

2017.013

Nil

Nil

Nil

Not Applicable

Cheung Wing Ching

1F, 1 floor, EF Block (Special Block), Department of OG, Prince of Wales Hospital, Shatin

3505 1764

cosycheung@cuhk.edu.hk

Department of OG

Hong Kong

YIU LEUNG CHAN

1F, 1 floor, EF Block (Special Block), Department of OG, Prince of Wales Hospital, Shatin

3505 3199

cylcps@yahoo.com.hk

Obstetric and gynaecology, CUHK

Hong Kong

A study on the relation between semen quality, compositions and microflora in male HBV carriers

A study on the relation between semen quality, compositions and microflora in male HBV carriers

男性乙型肝炎攜帶者的精液質量、組合物和微生物群落之間的關係

Hong Kong

Yes

2017-03-14

Joint CUHK-NTEC Clinical Research Ethics Committee

2017.013

Hepatitis B virus (HBV) carrier

semen quality

semen composition

semen microflora

Other

semen analysis, blood taking and filling in questionnaires

1. provide a semen sample (A portion of semen will be taken for routine analysis, rest of the sample is for research purposes).
2. take 5 – 10ml blood sample for hormonal test or other biochemical molecules (such as enzyme or amino acid). Blood taking may cause minimal pain and very minimal risk of infection.
3. Spend 5 – 10 minutes to fill in the questionnaire.

Nil

Nil

Nil

Nil

Nil

Nil

Nil

Nil

Nil

Chinese male

HBV carrier

40 non HBV carriers will also be recruited as a group of control.

genetic defects (Phenotypically abnormal)

azoospermia

18

60

Male

Observational

Not Applicable

Not Applicable

Not Applicable

Not Applicable

Other

This is not a drug trial

2018-01-23

307 HBV carrier & 40 healthy non HBV patients: totally 347

Not Yet Recruiting

To find out what is/are the major factor/s impair male fertility in chronical HBV carriers.

semen sampling, blood sampling and filling in a questionnaire about lifestyle

(1) at the day of semen analysis, (2) follow up for fertility outcome

Possibly minimize the viral infection/transmission outcome and maximize subfertility treatment outcome among male HBV carriers

semen sampling, blood sampling and filling in a questionnaire about lifestyle

(1) at the day of semen analysis, (2) follow up for fertility outcome

No

2020-07-06

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