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Trial History Detail on 2018-01-25

CUHK_CCRB00577

2018-01-11

Prospective

2017.133

Nil

Nil

Nil

Not Applicable

Cheung Wing Ching

1E, 1 Floor, EF Block (Special Block), Department of OG, Prince of Wales, Shatin, N.T.

3505 1764

cosycheung@cuhk.edu.hk

Department of OG

Hong Kong

Dr. CHUNG Pui Wah, Jacqueline

1F, 1 Floor, EF Block (Special Block), Department of OG, Prince of Wales, Shatin, N.T.

35051537

jacquelinechung@cuhk.edu.hk

Department of OG

Hong Kong

Adenomyosis in infertility patients and those with recurrent implantation failure

Adenomyosis in infertility patients and those with recurrent implantation failure

子宮腺肌症對不孕及體外受精之影響

Hong Kong

Yes

2017-04-01

Joint CUHK-NTEC Clinical Research Ethics Committee

2017.133

Adenomyosis

recurrent implantation failure

Procedure

1. 2D/ 3D transvaginal ultrasound examination or magnetic resonance imaging (MRI) will be performed to examine the uterus, ovaries and adenxal region.

2. Depending on clinical condition of individual patient, some may have to undergo further assessment with hysteroscopy and endometrial sampling. T

2.1 Patient will also be asked to come back for an endometrial sampling for endometrial assessment during 7 days after the LH surge (as detected using urine LH kit).

2.2 Hysteroscopy is a common gynaecological examination. The procedure will be performed under aseptic technique.

nil

nil

nil

nil

nil

nil

nil

nil

nil

18 to 45 years old

a diagnosis of clinically suspected and ultrasound/MRI diagnosis adenomyosis undergoing ART treatment

previous uterine surgery

uterine malformation

endometrial abnormalities like those with endometrial polyps, fibroids

refuse to join

18

45

Female

Observational

Not Applicable

Not Applicable

Not Applicable

Not Applicable

Other

This is not a drug trial

2018-01-17

50

Recruiting

explore the relationship between adenomyosis and recurrent implantation failure.

(1) 2D/3D Ultrasound or MRI, (2) Hysteroscopy, (3) Endometrial sampling

(1) & (2): ultrasound/ MRI and hysteroscopy will be performed by individual schedule, (3) Endometrial sampling: LH surge + 7 days

evaluate the overall incidence of adenomyosis in patient undergoing IVF treatment

(1) 2D/3D Ultrasound or MRI, (2) Hysteroscopy, (3) Endometrial sampling

(1) & (2): ultrasound/ MRI and hysteroscopy will be performed by individual schedule, (3) Endometrial sampling: LH surge + 7 days

evaluate the IVF stimulation, laboratory and reproductive outcome of those patients with adenomyosis, especially in those with recurrent implantation failure.

(1) Demographic data and detailed clinical history will be recorded, (2) 2D/3D transvaginal or magnetic resonance imaging

(1) At the time of recruitment, (2) ultrasound/ MRI will be performed by individual schedule

No

2020-07-06

ChiCTR1800014626

2018-01-16

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