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Trial Detail

CUHK_CCRB00574

2018-01-09

Prospective

CREC.2017.498-T

Department of Anaesthesia & Intensive Care, CUHK

Department of Anaesthesia & Intensive Care, CUHK

NA

Not Applicable

Winnie Samy

Department of Anaesthesia & Intensive Care,
4/F Main Clinical Block & Trauma Centre,
Prince of Wales Hospital,
Shatin
NT

3505 2735

wsamy@cuhk.edu.hk

Department of Anaesthesia & Intensive Care

Hong Kong

Manoj Kumar Karmakar

Department of Anaesthesia & Intensive Care,
4/F Main Clinical Block & Trauma Centre,
Prince of Wales Hospital,
Shatin
NT

3505 2735

karmakar@cuhk.edu.hk

Department of Anaesthesia & Intensive Care

Hong Kong

A Prospective Randomized Comparison of the Effects of Lidocaine and Ropivacaine on Block Dynamic after a Costoclavicular Brachial Plexus Block

A Prospective Randomized Comparison of the Effects of Lidocaine and Ropivacaine on Block Dynamic after a Costoclavicular Brachial Plexus Block

前瞻性隨機比較使用利多卡因(Lidocaine)和羅呱卡因(Ropivacaine)對肋鎖間的鎖骨下窩臂叢神經阻滯後阻滯動態的效果

Hong Kong

Yes

2017-11-14

Joint CUHK-NTEC Clinical Research Ethics Committee

CREC. 2017.498-T

Musculoskeletal disease of the upper limb that require surgery under regional anesthesia

Drug

To compare the onset of sensory-motor blockade in the ipsilateral upper extremity between two local anaesthetic drugs i.e. “lidocaine” and “ropivacaine” via the costoclavicular space for brachial plexus block (costoclavicular brachial plexus). Lidocaine and ropivacaine are commonly used local anesthetic agents in daily clinical practice for patients requiring to have surgery under local or regional anesthesia

Under ultrasound guidance, patient will receive either 1.5% lidocaine with adrenaline 25 ml, or 0.5% ropivacaine 25 ml injected at infraclavicular brachial plexus

Patient will receive either 1.5% lidocaine with adrenaline 25 ml, or 0.5% ropivacaine 25 ml

1 hour

once before operation

One group of patients will receive lidocaine with adrenaline and another group will receive ropivacaine.

Under ultrasound guidance, patient will receive either 1.5% lidocaine with adrenaline 25 ml, or 0.5% ropivacaine 25 ml injected for costoclavicular brachial plexus

Patient will receive either 1.5% lidocaine with adrenaline 25 ml, or 0.5% ropivacaine 25 ml

1 hour

once before operation

Patients who are between 20 to 70 years of age, of American Society of Anesthesiologists (ASA) status I to III, and planned for arm, forearm and hand surgery under regional anesthesia in Prince of Wales Hospital.

Patients who refuse regional anesthesia or unwilling to participate in the study; ASA physical status more than III; Pregnant patients; Patients with neuromuscular disorder; Prior surgery in the medial infraclavicular area on the same side of operation; Patients who are coagulopathic or taking anticoagulants; Patients suffering from dysaesthesia or chronic neuropathic pain at the site of surgery; History of local anesthetics allergy; Skin infection over the site of the block.

20

70

Both Male and Female

Interventional

Randomized

Prospective, randomized controlled trial

Active

Double-blind

Parallel

4

2018-02-01

86

Not Yet Recruiting

Proportion of patients achieving complete sensory and motor blockade at 30 minutes

complete sensory & motor block means sensory score =0 and motor score =0

at regular intervals for 45 minutes (5 min, 10 min, 15 min, 20 min, 30 min, 45 min) after the block

Time of readiness for surgery; Time to complete sensory and motor block; Sensory & motor scores at all the time points over all nerve distributions (median, radial, ulnar and musculocutaneous nerve); Proportion of patients achieving readiness for surgery at all time points; Paresthesis & discomfort

readiness for surgery (sensory score≤ 30 and motor score ≤1); complete sensory and motor block (sensory score = 0 and motor score = 0); parethesia (yes or no); degree of discomfort (verbal rating scale, 0-100, 0=no pain & 100= worst imaginable pain)

at regular intervals for 45 minutes (5 min, 10 min, 15 min, 20 min, 30 min, 45 min) after the block

No

2020-08-10

ChiCTR1800014387

2018-01-10

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