CUHK_CCT00057
2005-12-13
Retrospective
Not applicable
N/A
Nil
Nil
Prof. Dennis SC Lam
dennislam_cu_res@cuhk.edu.hk
Prof. Dennis SC Lam
dennislam_cu_res@cuhk.edu.hk
Identification of genes for high myopia
Not applicable
Yes
2004-02-28
Eye Diseases
Other
Nil
Nil
5 years
Nil
Inclusion criteria: Plan to carry out whole genome scan and linkage studies of 30 independent pedigrees of at least 3 generations, each with more than 10 members and 3 high myopia that we have recruited. None of these families have myopia associated disease such as Stickler's syndrome, Marfan syndrome and juvenile glaucoma.
Non-randomized
Active
Open label
Single group
2004-07-01
1500
Recruiting
Advancing knowledge in basic molecular genetics.
1. Affirm chromosomal loci linked to myopia. 2. Identify new myopia genes. 3. Reveal the frequencies of specific sequence alterations in the new putative myopia gene(s) in the local Chinese population. 4. Establish a basis to study interactive effects between environmental and genetic factors that contribute to myopia.
2015-06-23
Yes
Nil
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