CUHK_CCT00055
2005-12-14
Retrospective
not applicable
N/A
Nil
Nil
Prof. Dennis SC Lam
email dennislam_cu_res@cuhk.edu.hk
Prof. Dennis SC Lam
email dennislam_cu_res@cuhk.edu.hk
Identification of genes for high myopia using parent-offspring trios
not applicable
Yes
2004-05-13
Eye Diseases
Other
N/A
Carry out whole genome scan and linkage studies of 200 parent-offspring trios, generations, each with more than 10 members and 3 high myopia that we have recruited. None of these families have myopia associated diseases such as Stickler's syndrome, Marfan syndrome and juvenile glaucoma.
N/A
N/A
Inclusion criteria: At least one of the family members has myopia members at ≤-6.0D, or high myopia developed at an early age.
Non-randomized
Active
Open label
Single group
2004-07-01
600
Recruiting
To verify the chromosomal loci linked to myopia.
To establish a basis to study interactive effects between environmental and genetic factors that contribute to myopia.
2015-06-23
Yes
Nil
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