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Trial History Detail on 2014-07-22

CUHK_CCT00423

2014-07-22

Prospective

CRE-2012.235

Division of Neurology, Department of Medicine & Therapeutics,PWH,CUHK

Division of Neurology, Department of Medicine & Therapeutics, The Chinese University of Hong Kong

NA

Eva JY LIU

Division of Neurology, Dept of Medicine and Therapeutics,PWH

2632 1853

evajyliu413@gmail.com

Division of Neurology, Dept of Medicine and Therapeutics,PWH,CUHK

Ka Sing WONG

Division of Neurology, Dept of Medicine and Therapeutics,PWH

2632 3877

ks-wong@cuhk.edu.hk

Dept of Medicine and Therapeutics, PWH,CUHK

Effects of combining External Counterpulsation Therapy and Intermittent Theta Burst Stimulation on Corticomotor Excitability in healthy adults

Effects of combining External Counterpulsation Therapy and Intermittent Theta Burst Stimulation on Corticomotor Excitability in healthy adults

體外反搏及間歇型脈衝磁刺激聯合療法對健康人運動皮質興奮性的研究

NA

HK, CHINA

Yes

2012-06-05

Stroke

Device

transcranial magnetic stimulation

10 sessions for TBS

sham transcranial magnetic stimulation

12 healthy adults aged 18 or more years, with no neurological complaints, and no contraindications to ECP or TMS

1 Personal or family history of epilepsy.
2 Metal implant(s) in any part of body or head (excluding tooth fillings).
3 Implanted cardiac pacemaker, defibrillator, medication pump or any other implanted electronics.
4 Personal history of recurring headaches.
5 History of skull fracture, serious head injury, and any head or brain surgery.
6 History of malignancy.
7 Sustained hypertension (systolic >180mmHg or diastolic > 100mmHg).
8 Subject has thrombocytopenia (platelet count < 100,000/mm3 ).
9 Evidence of arteriovenous malformation, arteriovenous fistula or aneurysm.
10 Subject is unlikely to complete 3 sessions.
11 Subject is a pregnant female or a breast-feeding mother.

18

80

Both Male and Female

Interventional

Not Applicable

Placebo

Single-blind

Crossover

2014-07-27

12

Not Yet Recruiting

Mean non-conditioned MEP amplitude in non-dominant FDI and ADM at 4 time points (immediately before ECP, immediately after ECP, 5 minutes after iTBS, 20 minutes after iTBS) will be recorded to evaluate the change of cortical excitability.

Mean conditioned MEP amplitude in non-dominant FDI and ADM at 4 time points (immediately before ECP, immediately after ECP, 5 minutes after iTBS, 20 minutes after iTBS) will be recorded to evaluate the change of intracortical inhibition .

No

2016-08-30


No

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