CUHK_CCT00403
2014-04-08
Prospective
CRE-2013.618
Pending
The Chinese University of Hong Kong
N/A
Not Applicable
SHANG, Qing
Department of Medicine & Therapeutics, CUHK
2635 2217
qingshang@cuhk.edu.hk
The Chinese University of Hong Kong
HONG KONG S.A.R., CHINA
SHANG, Qing
Department of Medicine & Therapeutics, CUHK
2635 2217
qingshang@cuhk.edu.hk
The Chinese University of Hong Kong
HONG KONG S.A.R., CHINA
Reactive myocardial fibrosis related mechanical dyssynchrony in patients with hypertension – An early marker of myocardial involvement?
Reactive myocardial fibrosis related mechanical dyssynchrony in patients with hypertension – An early marker of myocardial involvement?
高血壓病人反應性心肌纖維化相關的心肌機械性不同步 – 心肌早期損傷的標誌?
Reactive myocardial fibrois & mechanical dyssynchorny
Hong Kong Special Administrative Region, People's Republic of China
Yes
2014-01-21
Hong Kong East Cluster Research Ethics Committee
2013.618
Hypertension
Other
None
N/A
N/A
N/A
N/A
N/A
N/A
N/A
N/A
N/A
N/A
Patients with hypertension which is defined as systolic blood pressure (SBP) ≥140mmHg or diastolic blood pressure (DBP) ≥90mmHg or the use of antihypertensive agents
Pregnancy, hypothyroidism, clinically significant renal disease (serum creatinine level ≥ 270ìmol/l), secondary hypertension and diabetes mellitus. Those with LV ejection fraction <50% or myocarditis, evidence of clinical coronary artery or pericardial disease, coronary revascularization, bundle-branch block, second-degree or higher atrioventricular block, atrial fibrillation, or greater than mild aortic or mitral valve diseases.
18 years
N/A
Both Male and Female
Observational
Non-randomized
Not Applicable
Not Applicable
Not Applicable
Other
N/A
2015-01-05
400
Unknown
Changes of fibrosis and dyssynchorny after 2 years
N/A
2016-11-15
ChiCTR-TCS-14004477
2014-04-10
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