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Trial History Detail on 2009-11-24

CUHK_CCT00044

2005-09-08

Retrospective

Nil

CUHK Direct Grant

N/a

n/a

Prof. Clement CY Tham

Dept. of Ophthalmology & Visual Sciences, Hong Kong Eye Hospital

2762 3196

clemtham@hkstar.com

The Chinese University of Hong Kong

Prof. Clement CY Tham

Dept. of Ophthalmology & Visual Sciences, Hong Kong Eye Hospital

2762 3196

clemtham@hkstar.com

The Chinese University of Hong Kong

A randomized controlled trial to compare lens extraction alone by phacoemulsification versus trabeculectomy alone in the treatment of medically-uncontrolled CACG without visually significant cataract.

A randomized controlled trial to compare lens extraction alone by phacoemulsification versus trabeculectomy alone in the treatment of medically-uncontrolled CACG without visually significant cataract.

Nil

Hong Kong

Yes

2005-03-18

Eye Diseases

Procedure

Cataract extraction

30 to 45 minutes

Trabeculectomy

Inclusion Criteria 1. Eyes with CACG as defined above 2. No significant cataract: VA better than 20/40, and not affecting activities of daily living 3. Patient able and willing to give informed consent to phacoemulsification or trabeculectomy, prior to randomization

Exclusion criteria 1. Single functional eye 2. Eyes with very advanced glaucomatous damage, defined as visual field loss threatening fixation, or cup-to-disc ratio of 0.9 and above 3. Patients refusing either cataract extraction or trabeculectomy 4. Previous intraocular surgery, with the exception of laser peripheral iridotomy and argon laser peripheral iridoplasty (ALPI).

n / a

n / a

Both Male and Female

Interventional

Randomized

Active

Open label

Parallel

2005-03-18

30

Recruiting

IOP

1. Number of IOP-lowering medications 2. Anesthetic method required, anesthetic complications, and subjective pain score by visual-analog scale 3. Peri-operative complications 4. Operative time, and Total operative time (including second-staged trabeculectomy performed for phaco-alone patients whose IOP is not sufficiently controlled, any other additional glaucoma procedures to further control IOP, and any procedures to handle complications of surgery) 5. Visual acuity (VA) 6. Angle status by indentation gonioscopy and ultrasound biomicroscopy (UBM) 7. Change in visual field by automated perimetry (Humphrey's) 8. Change in vertical cup-to-disc ratio of the optic nerve head 9. Rate of aqueous outflow by pneumatonometer measurements 10. Quality of Life (QOL) 11. Cost-effective analysis - including any additional procedures required to control IOP and cost of glaucoma drugs

No

2012-04-26


Yes

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