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Trial History Detail on 2014-01-22

CUHK_CCT00387

2014-01-14

Prospective

CRE-2013.600-T

Department of Paediatrics

Department of Paediatrics, The Chinese University of Hong Kong

N/A

Chun Ting Au

Department of Pediatrics, 6th Floor, Clinical Sciences Building, Prince of Wales Hospital, Shatin, Hong Kong

26322982

junau@cuhk.edu.hk

Department of Paediatrics, Prince of Wales Hospital, The Chinese University of Hong Kong

Albert Martin Li

Department of Pediatrics, 6th Floor, Clinical Sciences Building, Prince of Wales Hospital, Shatin, Hong Kong

26322917

albertmli@cuhk.edu.hk

Department of Paediatrics, Prince of Wales Hospital, The Chinese University of Hong Kong

A randomized study of intranasal corticosteroid for childhood primary snoring – endothelial function perspective

Impact of intranasal corticosteroid on endothelial function of children with primary snoring

類固醇噴鼻治療對原發性鼻鼾症兒童的血管內皮細胞功能之影響

intranasal corticosteroid on endothelial for endothelial function of children with primary snoring

Hong Kong

Yes

2013-12-13

primary snoring

Drug

budesonide 32mcg one spray per nostril once daily

4 months

N/A, watchful waiting as controls

(i) Hong Kong Chinese children and adolescents aged between 8-16 years.
(ii) Normal sleep study as documented on PSG (OAHI <1).
(iii) Non-smoker.
(iv) Written informed consent obtained from parents.

(i) Obesity, defined as having a body mass index (BMI) ≥95th percentile (corresponding to a z score of 1.645) of the local reference.[20]
(ii) Known medical conditions that could affect airway, BP control and endothelial function, for example cranio-facial, neuromuscular diseases and congenital heart disease.
(iii) Receiving medications that could alter BP control and endothelial function.
(iv) Upper respiratory tract or other infection within the past 4 weeks from recruitment.

8

16

Both Male and Female

Interventional

Randomized

Placebo

Single-blind

Parallel

2014-04-01

104

Not Yet Recruiting

flow-mediated dilatation of brachial artery

N/A

No

2015-08-17

ChiCTR-TRC-14004138


Yes

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