Trial Detail








Cheng Pak Wing 鄭柏榮

Department of Psychiatry, G/F, Multi-Centre, Tai Po Hospital, Tai Po, N.T., Hong Kong


Department of Psychiatry, the Chinese University of Hong Kong

Linda CW Lam 林翠華

Department of Psychiatry, G/F, Multi-Centre, Tai Po Hospital, Tai Po, N.T., Hong Kong


Department of Psychiatry, the Chinese University of Hong Kong

An exploratory study on the effects of Integrated Attention training for healthy older Chinese adults with subjective cognitive complaints but no clinical dementia

A study on the effects of Integrated Attention training for healthy older chinese adults



Hong Kong



mild cognitive impairment


This will be a single blind Randomized Controlled Trial of 6 months duration. Older Chinese adults /9aged 60 or above) with subjective cognitive complaints without dementia will be randomized into 2 intervention groups. The intervention groups comprised of Integrated Attention Training Group(A) and Psycoeducation Group (C). Each participant will participate in regular activities arranged by the participating elderly centres for first 3 months and practices at home for next 3 months.

Six months

Description of treatments
1. The integrated attention (A) training group will have training on different attention tasks. Basic elements will include practice of focused attention on internal cues, selective attention, divided attention and everyday functional tasks focus on attention.
2. The controlled (C) group will be received health -related education program on different health related topics.
Intervention schedule
The intervention will be conducted in two phases. 1. Induction phase – There will be a total of 12 training (once weekly) sessions over a 12 week period. Each training session will last for 45 minutes including introduction and closing. 2. Intervention phase - After the induction course has been completed, subjects will be advised to practice the respective training for not less than 30 minutes per day, and not less than 3 days per week. A practice manual will be offered to participants to aid home practice. To booster adherence to program, the intervention instructors will provide a refresher lesson every month. A log book will be used to keep track of the adherence. Research staffs will phone up participants every two weeks to remind continuation of program.

1. Subjects aged 60 or above.
2. Subjective cognitive complaints
3. ability to communicate in Cantonese

1. Clinical diagnosis of dementia, according to DSM-Ⅳ
2. Had a chronic psychiatric illness or an acute episode of major depression
3. Taking a psychotropic or other medication known to affect cognition (e.g. benzodiazepines, anti-dementia medication, etc.)
4) Clinically depressed, assessed by the Hamilton Depression Rating Scale
5) Attending regular cognitive training or other intervention for brain health during the study period
6) History of major neurological deficit including history of stroke, transient ischemic attack or traumatic brain injury
7) Significant communicative impairments

60 years


Both Male and Female









Clinical Dementia Rating (CDR) sum of boxes scores. The CDR is a semi-structured clinical interview for the severity of cognitive impairment rated along six dimensions of cognition and function. CDR indicates global cognition reflecting changes in overall function from very early stages of cognitive decline

1) Cognitive assessment included digit span, visual span, category verbal fluency (CVFT), trail making tests, mini mental state examination (MMSE), Alzheimer’s Disease Assessment Scale- Cognitive (ADAS-Cog) and Attention Network Test (ANT)
2) Subjective cognitive assessment (SCC) measured by Memory Inventory for the Chinese (MIC). It is a 22 item questionnaire exploring subjective cognitive problems in everyday activities.

3) Depressive and anxiety symptomatology was assessed with the Hamilton Depression Rating Scale and Hamilton Anxiety Rating Scale





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