CUHK_CCT00320
2012-05-17
Prospective
Nil
Nil
Nil
Nil
Alex Pui Wai LEE
Division of Cardiology, Department of Medicine & Therapeutics, The Chinese University of Hong Kong, Shatin, N.T., Hong Kong
852-2632 3140
alexpwlee@cuhk.edu.hk
Department of Medicine & Therapeutics, The Chinese Univerity of Hong Kong
Qing SHANG
Division of Cardiology, Department of Medicine & Therapeutics, The Chinese University of Hong Kong, Shatin, N.T., Hong Kong
852-2632 3840
qingshang@cuhk.edu.hk
Department of Medicine & Therapeutics, The Chinese Univerity of Hong Kong
Cardiovascular Reserve in Patients with Systemic Autoimmune Diseases
Cardiovascular Reserve in Patients with Systemic Autoimmune Diseases
Nil
Hong Kong SAR, China
Yes
2012-03-21
Rheumatic diseases
Other
None
N/A
N/A
N/A
Patients with SLE or PsA, Control subjects who are considered to have a low probability of coronary artery disease on clinical grounds and have a normal exercise stress echocardiogram.
Hypertension, significant atrial or ventricular arrhythmia, significant valvular diseases (>moderate severity), significant coronary artery disease, prior history of myocardial infarction, impaired LV systolic function (ejection fraction<50%, or any regional wall motion abnormality), pericardial disease and unable to exercise.
18 years
N/A
Both Male and Female
Observational
Non-randomized
Not Applicable
Not Applicable
Parallel
2012-07-04
150
Not Yet Recruiting
1. Changes in resting cardiac function and functional reserve during exercise in 3-dimensional planes
2. Increased arterial stiffness in resting and impaired vascular reserve during exercise
3. Association among early cardiovascular dysfunction, impaired functional reserve during exercise and biomarkers
N/A
2014-11-24
Yes
Nil
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