CUHK_CCT00281
2011-10-11
Retrospective
None
General Research Fund (GRF)
General Research Fund (GRF)
N/A
Skiva Chan
Dept of Medicine & Therapeutics, CUHK
26463200
skivachan@cuhk.edu.hk
PWH
Cheuk-Man YU
Dept of Medicine & Therapeutics, CUHK
26323594
cmyu@cuhk.edu.hk
PWH
Establishment of a Comprehensive Model that Predicts Favorable Response after Cardiac Resynchronization Therapy
Establishment of a Comprehensive Model that Predicts Favorable Response after Cardiac Resynchronization Therapy
N/A
Hong Kong
Yes
2011-01-11
Heart Failure
Other
None
N/A
N/A
N/A
Patients with HF due to systolic dysfunction who are suitable candidates for CRT according to the current ACC/AHA/ESC guidelines will be enrolled, namely, patients with NYHA class III or IV, ejection fraction <35%, prolonged QRS duration of >120ms, and refractory to optimal medical therapy including neurohormonal blockers.2 Patients with atrial fibrillation are accepted for CRT from current guideline and hence will be induced. However, measures will be taken to ensure a high percentage of biventricular pacing (e.g. aggressive beta-blockers, digoxin etc).
1.HF with LV ejection fraction > and = 35%
2.Any major illnesses with life expectancy <6months, e.g., terminal malignancy
3.Patients unwilling to participate into the study or refuse or deemed unsuitable for CRT
18
N/A
Both Male and Female
Observational
Not Applicable
Not Applicable
Open label
Not Applicable
2011-02-16
300
Recruiting
To develop and validate a comprehensive clinical model with a scoring system that will increase the response rate of CRT
To improve the overall response rate of CRT from primarily a clinical perspective to secondarily a cardiac functional perspective
2014-11-29
ChiCTR-ONC-11001650
2011-11-03
Yes
N/A
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