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Trial History Detail on 2011-02-08

CUHK_CCT00275

2010-11-10

Retrospective

Nil

Department of Anaesthesia and Intensive Care, CUHK

Department of Anaesthesia and Intensive Care, CUHK

nil

Dr Tsang, Kristie Ho Sze

Department of Anaesthesia and Intensive Care, CUHK, Prince of Wales Hospital

26322734

kristie@cuhk.edu.hk

Associate Consultant, Department of Anaesthesia and Intensive Care, Prince of Wales Hospital

Dr Chan, Simon Kin Cheong

Department of Anaesthesia and Intensive Care, Prince of Wales Hosiptal

2632 2734

simonkcchan@cuhk.edu.hk

Consultant, Department of Anaesthesia and Intensive Care, Prince of Wales Hospital

Analgesic efficacy of intra-articular magnesium after arthroscopic anterior cruciate ligament reconstruction

Analgesic efficacy of intra-articular magnesium after arthroscopic anterior cruciate ligament reconstruction

Nil

Hong Kong

Yes

2008-01-08

Arthroscopic anterior cruciate ligament reconstruction surgery of knee joint

Drug

Intra-articular injection of magnesium for post-operative pain control

Once off

Placebo control

Adult patients of ASA I-II and mentally capable for informed consent, who are scheduled for elective arthroscopic ACL reconstruction will be recruited in the study

•ASA III or above
•Impaired renal or liver function
•History of chronic pain or substance abuse
•Known hypersensitivity to sulphur drug or NSAIDs
•Contraindicated for NSAIDs, such as known hypersensitivity, past history of peptic ulcer disease or platelet dysfunction.
•Pregnancy or lactation in female patients
•Contraindications for administration of MgSO4, such as heart block, myocardial damage, myopathy or neurological disorders
•Concomitant medications: digitalis, calcium channel blocker, central nervous system depressants

18 years old

no specific age maximum

Both Male and Female

Interventional

Randomized

Placebo

Double-blind

Parallel

2008-05-01

42 patient

Complete

Pain score at rest. on movement and on weight bearing

Sedation, muscle weakness and magnesium level.

No

2010-11-10

ChiCTR-TRC-10001098

2010-12-01


Yes

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