CUHK_CCT00156
2008-02-15
Prospective
Not applicable
N/A
Nil
Nil
Dr. Anita SY Ng
anitang@cuhk.edu.hk
Prof. Dennis SC Lam
dennislam_cu_res@cuhk.edu.hk
Intravitreal injection of Bevacizumab (Avastin®) as an adjunctive therapy of pterygium surgery to prevent recurrence: A pilot study
Not applicable
Yes
2008-01-31
pterygium
Procedure
Intravitreal injection of Bevacizumab (Avastin®) after surgical excision of pterygium
one injection immediately after surgical excision of pterygium
There is no comparative treatment as this is a pilot study. We will observe the recurrence rate of pterygium being treated with adjunctive intravitreal Avastin injection and design a randomized controlled trial in the future.
Inclusion criteria: 1. Age 18 years or above 2. Eye with single-head primary or secondary pterygium 3. Patient able and willing to give informed consent to the pterygium surgery with intravitreal injections of bevacizumab Exclusion criteria: 1. Single functional eye 2. Pregnant patients 3. Use of anticoagulants or antiplatelet therapy other than aspirin / NSAID within 14 days of surgery.
Non-randomized
Uncontrolled
Open label
Single group
2008-03-01
50 eyes
Not Yet Recruiting
Recurrence of pterygium, up to 24 months post op
- Visual acuity (VA) - Intraocular pressure (IOP) - Corneal endothelial cell counts - Corneal astigmatism - Any complications from the injections
2013-01-14
Yes
Nil
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