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Trial History Detail on 2008-02-15

CUHK_CCT00155

2008-02-15

Prospective

Not applicable

N/A

Nil

Nil

Dr. Anita SY Ng

anitang@cuhk.edu.hk

email

Prof. Dennis SC Lam

dennislam_cu_res@cuhk.edu.hk

email

Post phacoemulsification cystoid macular edema: Incidence, rick factors and efficacy of non-steroidal anti-inflammatory drug in its prevention

Not applicable

Yes

2007-11-10

phacoemulsification cystoid macular edema

Drug

Use of non-steroidal anti-inflammatory eye drop (Acular) in preventing post-cataract surgery cystoid macula edema

4 weeks use of Acular after cataract surgery

Study group will receive ketorolac tromethamine 0.5% (Acular) eye drop Control group will receive placebo ie. 0.9%normal saline eye drop

Inclusion criteria 1. Senile cataract in patients older than 50 years old 2. Adequate fundal view for OCT measurement before cataract surgery 3. pre-op OCT could be obtained with signal strength 6.0 4. fully informed consent Exclusion criteria 1. pre-existing macular edema 2. any conditions known to cause macular edema, including retinal vein or artery occlusion, uveitis, premacular fibrosis, retinitis pigmentosa, macular hole and choroidal neovascularisation 3. significant ocular diseases such as glaucoma 4. pre-existing refractive error of >-6.00 diopters or +6.00 diopters 5. systemic medications that may affect retinal thickening such as steroid or diuretics 6. single eye patients 7. For diabetic patients, history of intravitreal or sub-Tenon¡¦s capsule injection or triamcinolone acetonide.

Randomized

Placebo

Double-blind

Parallel

2008-03-01

140

Not Yet Recruiting

1. Macular thickness and central foveal volume assessed by OCT

2. Best corrected visual acuity (ETDRS chart) 3. risk factors for development of CME ( e.g. phaco time, phaco energy etc.) 4. development of posterior vitreous detachment

No

2012-04-17


Yes

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