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Trial History Detail on 2009-11-19

CUHK_CCT00154

2008-02-15

Prospective

Nil

Department funding from DOVS, CUHK (for the drug bevacizumab(avastin))

Nil

Nil

Dr. Felix CH Li

email xil@dr.com

Prof. Dennis SC Lam

email dennislam_cu_res@cuhk.edu.hk

Trabeculectomy with adjunctive intravitreal injection of bevacizumab (avastin). A preliminary study.

Nil

Yes

2007-08-29

Glaucoma

Other

Drug+Procedure

Trabeculectomy with intravitreal injection of Bevacizumab (Avastin)

30-60 mins

No control or comparative treatment for this study

Inclusion Criteria 1. Age 18 years or above 2. Eyes that undergo trabeculectomy 3. Patient able and willing to give informed consent to needling with intra-vitreal injection of bevacizumab.

Exclusion criteria 1. Single functional eye 2. Pregnant patients 3. Patients refusing trabeculectomy or bevacizumab injection 4. Use of anticoagulants or antiplatelet therapy other than aspirin/NSAIDs within 14 days of surgery. 5. Presence of a nonhealing wound, ulcer, fracture, or any medical condition associated with bleeding

Non-randomized

Uncontrolled

Open label

Single group

2008-03-01

30

Not Yet Recruiting

Intra-ocular pressure

1. Bleb morphology (with photographic record) 2. Visual acuity 3. Number of IOP-lowering medications 4. Corneal clarity and corneal endothelial cell count (by specular microscopy) 5. Lens status 6. Progression in glaucomatous optic neuropathy and visual field loss 7. Any complications from surgery

No

2012-04-17


Yes

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